A fast-Fourier-transform method of topography and interferometry is proposed. By computer processing of a noncontour type of fringe pattern, automatic discrimination is achieved between elevation and depression of the object or wave-front form, which has not been possible by the fringe-contour-generation techniques. The method has advantages over moire topography and conventional fringe-contour interferometry in both accuracy and sensitivity. Unlike fringe-scanning techniques, the method is easy to apply because it uses no moving components.

Fourier-transform method of fringe-pattern analysis for computer-based topography and interferometry

We examine the current performance and future demands of interconnects to and on silicon chips. We compare electrical and optical interconnects and project the requirements for optoelectronic and optical devices if optics is to solve the major problems of interconnects for future high-performance silicon chips. Optics has potential benefits in interconnect density, energy, and timing. The necessity of low interconnect energy imposes low limits especially on the energy of the optical output devices, with a ~ 10 fJ/bit device energy target emerging. Some optical modulators and radical laser approaches may meet this requirement. Low (e.g., a few femtofarads or less) photodetector capacitance is important. Very compact wavelength splitters are essential for connecting the information to fibers. Dense waveguides are necessary on-chip or on boards for guided wave optical approaches, especially if very high clock rates or dense wavelength-division multiplexing (WDM) is to be avoided. Free-space optics potentially can handle the necessary bandwidths even without fast clocks or WDM. With such technology, however, optics may enable the continued scaling of interconnect capacity required by future chips.

Device Requirements for Optical Interconnects to Silicon Chips

Single-molecule surface-enhanced Raman scattering (SM-SERS) is one of the vital applications of plasmonic nanoparticles. The SM-SERS sensitivity critically depends on plasmonic hot-spots created at the vicinity of such nanoparticles. In conventional fluid-phase SM-SERS experiments, plasmonic hot-spots are facilitated by chemical aggregation of nanoparticles. Such aggregation is usually irreversible, and hence, nanoparticles cannot be re-dispersed in the fluid for further use. Here, we show how to combine SM-SERS with plasmon polariton-assisted, reversible assembly of plasmonic nanoparticles at an unstructured metal–fluid interface. One of the unique features of our method is that we use a single evanescent-wave optical excitation for nanoparticle assembly, manipulation and SM-SERS measurements. Furthermore, by utilizing dual excitation of plasmons at metal–fluid interface, we create interacting assemblies of metal nanoparticles, which may be further harnessed in dynamic lithography of dispersed nanostructures. Our work will have implications in realizing optically addressable, plasmofluidic, single-molecule detection platforms. Plasmonic hot-spot generation in solution is not reversible for single-molecule surface-enhanced Raman scattering, which limits its applications. Patra et al.tackle this problem by integrating this technique with thermo-plasmon-assisted reconfiguration of nanoparticles at a metal–fluid interface.

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Plasmofluidic single-molecule surface-enhanced Raman scattering from dynamic assembly of plasmonic nanoparticles

The fact that light carries both linear and angular momentum is well-known to physicists. One application of the linear momentum of light is for optical tweezers, in which the refraction of a laser beam through a particle provides a reaction force that draws the particle towards the centre of the beam. The angular momentum of light can also be transfered to particles, causing them to spin. In fact, the angular momentum of light has two components that act through different mechanisms on various types of particle. This Review covers the creation of such beams and how their unusual intensity, polarization and phase structure has been put to use in the field of optical manipulation.

Tweezers with a twist

The silicon chip has been the mainstay of the electronics industry for the last 40 years and has revolutionized the way the world operates. Today, a silicon chip the size of a fingernail contains nearly 1 billion transistors and has the computing power that only a decade ago would take up an entire room of servers. As the relentless pursuit of Moore's law continues, and Internet-based communication continues to grow, the bandwidth demands needed to feed these devices will continue to increase and push the limits of copper-based signaling technologies. These signaling limitations will necessitate optical-based solutions. However, any optical solution must be based on low-cost technologies if it is to be applied to the mass market. Silicon photonics, mainly based on SOI technology, has recently attracted a great deal of attention. Recent advances and breakthroughs in silicon photonic device performance have shown that silicon can be considered a material onto which one can build optical devices. While significant efforts are needed to improve device performance and commercialize these technologies, progress is moving at a rapid rate. More research in the area of integration, both photonic and electronic, is needed. The future is looking bright. Silicon photonics could provide low-cost opto-electronic solutions for applications ranging from telecommunications down to chip-to-chip interconnects, as well as emerging areas such as optical sensing technology and biomedical applications. The ability to utilize existing CMOS infrastructure and manufacture these silicon photonic devices in the same facilities that today produce electronics could enable low-cost optical devices, and in the future, revolutionize optical communications

http://ieeexplore.ieee.org/iel5/6668/34347/01638290.pdf

Silicon photonics

Vortex beams with dierent topological charge usually have dierent proles and radii of peak intensity. This introduces a degree of complexity the fair study of the nature of optical OAM (orbital angular momentum). To avoid this, we introduced a new approach by creating a perfect vortex beam using an annular illuminating beam with a xed intensity prole on an SLM that imposes a chosen topological charge. The radial intensity prole of such an experimentally created perfect vortex beam is independent to any given integer value of its topological charge. The well-dened OAM density in such a perfect vortex beam is probed by trapping microscope particles. The rotation rate of a trapped necklace of particles is measured for both integer and non-integer topological charge. Experimental results agree with the theoretical prediction. With the exibility of our approach, local OAM density can be corrected in situ to overcome the problem of trapping the particle in the intensity hotspots. The correction of local OAM density in the perfect vortex beam therefore enables a single trapped particle to move along the vortex ring at a constant angular velocity that is independent of the azimuthal position. Due to its particular nature, the perfect vortex beam may be applied to other studies in optical trapping of particles, atoms or quantum gases.

/pdf/optical-trapping-with-a-perfect-vortex-beam-177kz30ieu.pdf

Optical trapping with a perfect vortex beam

The use of ultrashort femtosecond pulsed lasers to effect membrane permeabilisation and initiate both optoinjection and transfection of cells has recently seen immense interest. We investigate femtosecond laser-induced membrane permeabilisation in mammalian cells as a function of pulse duration, pulse energy and number of pulses, by quantifying the efficiency of optoinjection for these parameters. Depending on pulse duration and pulse energy we identify two distinct membrane permeabilisation regimes. In the first regime a nonlinear dependence of order 3.4-9.6 is exhibited below a threshold peak power of at least 6 kW. Above this threshold peak power, the nonlinear dependence is saturated resulting in linear behaviour. This indicates that the membrane permeabilisation mechanism requires efficient multiphoton absorption to produce free electrons but once this process saturates, linear absorption dominates. Our experimental findings support a previously proposed theoretical model and provide a step towards the optimisation of laser-mediated gene delivery into mammalian cells.

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Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells.

This letter demonstrates how the use of an annular beam can significantly reduce the detected fluorescence from optical components within a Raman spectroscopic arrangement. The fluorescence from the excitation beam has a reduced generation and collection efficiency compared to the standard Gaussian beam. Crucially, the Raman signal from the annular beam is collected through the dark center of the excitation light field. This robust and simple technique may be immediately applied to all Raman configurations and may find broader applicability for any spectroscopic methodology which utilizes a high numerical aperture lens and requires the detected fluorescence to be suppressed.

Fluorescence suppression within Raman spectroscopy using annular beam excitation

Impedance matching refers to the suppression of reflected radiation from an interface and is a concept that applies right across the electromagnetic spectrum. In particular it has come to prominence in relation to the propagation of light in metallic structures and associated meta-materials. Whilst established for microwaves and electrical circuits, this concept has only very recently been observed in the optical domain, yet is not well defined or understood. We present a framework to elucidate the concept of optical impedance. We describe using a scattering matrix approach the characteristic, iterative, image and wave impedances of an optical system. With a numerical model, we explore each form of impedance matching in metal-dielectric structures. Thin gold layers may extend the concept of Brewster's angle to normal incidence and s polarization. Optical impedance for recently realized metallic gold nanopillars which has shown negative permeability is also explored and we show that current measurements are inconclusive to robustly state its characteristic impedance is matched to the vacuum.

Optical impedance of metallic nano-structures.

Raman spectroscopy has proven to be an indispensable technique for the identification of various types of analytes due to the fingerprint vibration spectrum obtained. Paper microfluidics has also emerged as a low cost, easy to fabricate and portable approach for point of care testing. However, due to inherent background fluorescence, combining Raman spectroscopy with paper microfluidics is to date an unmet challenge in the absence of using surface enhanced mechanisms. We describe the first use of wavelength modulated Raman spectroscopy (WMRS) for analysis on a paper microfluidics platform. This study demonstrates the ability to suppress the background fluorescence of the paper using WMRS and the subsequent implementation of this technique for pharmaceutical analysis. The results of this study demonstrate that it is possible to discriminate between both paracetamol and ibuprofen, whilst, also being able to detect the presence of each analyte quantitatively at nanomolar concentrations.

/pdf/quantitative-detection-of-pharmaceuticals-using-a-52w52m6e6t.pdf

Michael Mazilu

Papers

Optical trapping with a perfect vortex beam

Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells.

Fluorescence suppression within Raman spectroscopy using annular beam excitation

Optical impedance of metallic nano-structures.

Quantitative Detection of Pharmaceuticals Using a Combination of Paper Microfluidics and Wavelength Modulated Raman Spectroscopy