M
Michael Paul Ferro
Publications - 12
Citations - 213
Michael Paul Ferro is an academic researcher. The author has contributed to research in topics: Alkyl & Moiety. The author has an hindex of 5, co-authored 12 publications receiving 205 citations.
Papers
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Journal ArticleDOI
1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2.
Zhihua Sui,Jihua Guan,Michael Paul Ferro,Kathy McCoy,Michael P. Wachter,William V. Murray,Monica Singer,Michele Steber,Dave M. Ritchie,Dennis C. Argentieri +9 more
TL;DR: Novel 1,3-diarylcycloalkanopyrazoles 1, and diphenyl hydrazides 2 were identified as selective inhibitors of cyclooxygenase-2 and SAR of both phenyl rings in 1 and 2, and the aliphatic ring in 1 will be discussed.
Patent
Pharmacologically active 1,5-diaryl-3-substituted pyrazoles and method for synthesizing the same
TL;DR: In this paper, a method of pyrazoles preparation, compositions containing the same and methods of their use are disclosed, which are useful in alleviating inflammatory and cardiovascular disorders in mammals.
Patent
1,3- and 2,3-diarylcycloalkano and cycloalkeno pyrazoles as selective inhibitors of cyclooxygenase-2 and antiinflammatory agents
TL;DR: In this paper, the 1,3 and 2,3-diarylpyrazole anti-inflammatory compounds of the general formulae were selected from the group consisting of hydrogen, halogen, (C1 -C6)alkyl, (c1 -c6)oxy, nitro, amino, amino amino, hydroxy, trifluoro, --S(C1-C6), S(C 1 -C 6), --SO 2 (C 1-C 6) and the fused moiety Q is a group selected from a
Patent
1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use
TL;DR: In this article, a method of pyrazoles preparation, compositions containing the same and methods of their use are disclosed, which are useful in alleviating inflammatory and cardiovascular disorders in mammals.
Journal ArticleDOI
1,3-Diarylcycloalkanopyrazoles and Diphenyl Hydrazides as Selective Inhibitors of Cyclooxygenase-2.
Zhihua Sui,Jihua Guan,Michael Paul Ferro,Kathy McCoy,Michael P. Wachter,William V. Murray,Monica Singer,Michele Steber,Dave M. Ritchie,Dennis C. Argentieri +9 more
TL;DR: In this paper, the 1,3-diaryl substitution pattern of pyrazole ring in 1 differentiates these compounds from most of the known selective COX-2 inhibitors that contain two aryl rings at the adjacent positions on a heterocyclic or a phenyl ring.