M
Michael R. Gillings
Researcher at Macquarie University
Publications - 208
Citations - 13821
Michael R. Gillings is an academic researcher from Macquarie University. The author has contributed to research in topics: Integron & Gene. The author has an hindex of 54, co-authored 194 publications receiving 10735 citations. Previous affiliations of Michael R. Gillings include University of New England (Australia).
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Journal ArticleDOI
Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution
Michael R. Gillings,William H. Gaze,Amy Pruden,Kornelia Smalla,James M. Tiedje,Yong-Guan Zhu +5 more
TL;DR: It is suggested that the relative abundance of the clinical class 1 integron-integrase gene, intI1, is a good proxy for pollution because it is linked to genes conferring resistance to antibiotics, disinfectants and heavy metals.
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Continental-scale pollution of estuaries with antibiotic resistance genes
Yong-Guan Zhu,Yi Zhao,Bing Li,Chu-Long Huang,Si-Yu Zhang,Shen Yu,Yongshan Chen,Tong Zhang,Michael R. Gillings,Jian-Qiang Su +9 more
TL;DR: The strong correlations of identified resistance genes with known mobile elements, network analyses and partial redundancy analysis all led to the conclusion that human activity is responsible for the abundance and dissemination of these ARGs.
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Spatial scaling of microbial eukaryote diversity
Jessica L. Green,Jessica L. Green,Andrew J. Holmes,Mark Westoby,Ian Oliver,David A. Briscoe,Mark Dangerfield,Michael R. Gillings,Andrew J. Beattie +8 more
TL;DR: In this article, the authors present quantitative estimates of microbial community turnover at local and regional scales using the largest spatially explicit microbial diversity data set available (> 10(6) sample pairs).
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Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens
H. W. Stokes,Michael R. Gillings +1 more
TL;DR: It is argued that human activities are exacerbating the problem of resistance to antibiotics by increasing the tempo of LGT and bacterial evolution for many traits that are important to humans.
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Integrons: Past, Present, and Future
TL;DR: This review examines the functions and activities of integrons before the antibiotic era and shows how antibiotic use selected particular integrons from among the environmental pool of these elements, such that integrons carrying resistance genes are now present in the majority of Gram-negative pathogens.