M
Michael S. Foulk
Researcher at Brown University
Publications - 10
Citations - 210
Michael S. Foulk is an academic researcher from Brown University. The author has contributed to research in topics: Sciara & DNA replication. The author has an hindex of 6, co-authored 10 publications receiving 173 citations. Previous affiliations of Michael S. Foulk include Mercyhurst University.
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Journal ArticleDOI
Characterizing and controlling intrinsic biases of Lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins
TL;DR: It is reported that λ-exo does not efficiently digest G-quadruplex (G4) structures in a plasmid, and it is demonstrated that use of Na(+) instead of K(+) in the κ(+) digestion buffer reduced the effect of G4s on λ -exo digestion and ways to increase both the sensitivity and specificity of NS-seq are discussed.
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Phytobilin biosynthesis: the Synechocystis sp. PCC 6803 heme oxygenase-encoding ho1 gene complements a phytochrome-deficient Arabidopsis thalianna hy1 mutant.
Robert D. Willows,Sandra M. Mayer,Michael S. Foulk,Alison DeLong,Kimberly Hanson,Joanne Chory,Samuel I. Beale +6 more
TL;DR: The results indicate that Synechocystis sp.
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The hunt for origins of DNA replication in multicellular eukaryotes
TL;DR: Several methods have been used recently to map ORIs in metazoan genomes with the hope that features for ORI specification might emerge.
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Ecdysone induces transcription and amplification in Sciara coprophila DNA puff II/9A
Michael S. Foulk,Chun Liang,Nan Wu,Hannah G. Blitzblau,Heidi S. Smith,Daniel Alam,Maneesh Batra,Susan A. Gerbi +7 more
TL;DR: The results implicate ecdysone in the regulation of DNA amplification in Sciara and suggest the ecDysone receptor may be the elusive amplification factor, which would be a new role for this transcription factor.
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High contiguity de novo genome assembly and DNA modification analyses for the fungus fly, Sciara coprophila, using single-molecule sequencing.
John M. Urban,John M. Urban,Michael S. Foulk,Michael S. Foulk,Jacob E. Bliss,C Michelle Coleman,Nanyan Lu,Reza Mazloom,Susan J. Brown,Allan C. Spradling,Susan A. Gerbi +10 more
TL;DR: In this article, the first draft genome sequence for Sciara coprophila was presented, which was used to find an optimal assembly using 27 metrics assessing contiguity, gene content, and dataset concordance.