M
Michael V. Tenditnik
Publications - 5
Citations - 122
Michael V. Tenditnik is an academic researcher. The author has contributed to research in topics: Autophagy & Neuroprotection. The author has an hindex of 3, co-authored 5 publications receiving 46 citations.
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Journal ArticleDOI
Therapeutic activation of autophagy by combined treatment with rapamycin and trehalose in a mouse MPTP-induced model of Parkinson's disease.
Alexander B. Pupyshev,Maria A. Tikhonova,Anna A. Akopyan,Michael V. Tenditnik,Nina I. Dubrovina,Tatyana A. Korolenko +5 more
TL;DR: The autophagy activation through different pathways by the combination of rapamycin and trehalose reverses both neuronal dopaminergic and behavioral deficits in vivo and seems to be a promising therapy for PD‐like pathology.
Journal ArticleDOI
Evaluating the Effects of Grain of Isogenic Wheat Lines Differing in the Content of Anthocyanins in Mouse Models of Neurodegenerative Disorders.
Maria A. Tikhonova,Olesya Yu. Shoeva,Michael V. Tenditnik,Marina V. Ovsyukova,Anna A. Akopyan,Nina I Dubrovina,Tamara G. Amstislavskaya,Elena K. Khlestkina +7 more
TL;DR: Anthocyanin-rich wheat is suggested as a promising source of functional nutrition at the early stages of neurodegenerative disorders, including Alzheimer's disease and Parkinson’s disease.
Journal ArticleDOI
Effects of Grape Polyphenols on the Life Span and Neuroinflammatory Alterations Related to Neurodegenerative Parkinson Disease-Like Disturbances in Mice.
Maria A. Tikhonova,Nadezhda G Tikhonova,Michael V. Tenditnik,Marina V. Ovsyukova,Anna A. Akopyan,Nina I Dubrovina,Tamara G. Amstislavskaya,Elena K. Khlestkina +7 more
TL;DR: In the transgenic PD model, the grape polyphenol (GP) diet enhanced memory reconsolidation and diminished memory extinction in a passive avoidance test and is recommended as promising functional nutrition for aging people and patients with neurodegenerative disorders.
Journal ArticleDOI
Neuroprotective Effects of Ceftriaxone Involve the Reduction of Aβ Burden and Neuroinflammatory Response in a Mouse Model of Alzheimer’s Disease
Maria A. Tikhonova,Tamara G. Amstislavskaya,Ying-Jui Ho,Anna A. Akopyan,Michael V. Tenditnik,Marina V. Ovsyukova,Alim Bashirzade,Nina I. Dubrovina,Lyubomir I. Aftanas +8 more
TL;DR: In this article, the effects of CEF on behavior, Aβ deposition, and associated neuroinflammation using another model of an early AD-like pathology induced by Aβ were determined.
Journal ArticleDOI
Treatment with Autophagy Inducer Trehalose Alleviates Memory and Behavioral Impairments and Neuroinflammatory Brain Processes in db/db Mice.
Tatiana A. Korolenko,Nina I. Dubrovina,Marina V. Ovsyukova,N. P. Bgatova,Michael V. Tenditnik,Alexander B. Pupyshev,Anna A. Akopyan,N. V. Goncharova,Chih-Li Lin,Evgeny L. Zavjalov,Maria A. Tikhonova,Tamara G. Amstislavskaya +11 more
TL;DR: In this article, the effect of trehalose on brain autophagy and behavior in a genetic model of diabetes with signs of neuronal damage (db/db mice) was studied.