Showing papers by "Michael W. Salter published in 2001"

TL;DR: Insight is given into the upregulation of theNMDA receptor by Src family tyrosine kinases, which bind to scaffolding proteins in the NMDA receptor complex, which is required for long-term potentiation in the CA1 region of the hippocampus.

TL;DR: It is shown that the focal adhesion kinase CAKbeta/Pyk2 upregulated NMDAR function by activating Src in CA1 hippocampal neurons, which may depend upon downstream activation of Src to upregulate NMDA receptors.

TL;DR: Results from the use of this method have already pointed to a previously unsuspected differential role for synaptic versus extrasynaptic NMDA receptors in lasting synaptic potentiation.