M
Michael Weig
Researcher at University of Göttingen
Publications - 51
Citations - 2299
Michael Weig is an academic researcher from University of Göttingen. The author has contributed to research in topics: Candida glabrata & Candida albicans. The author has an hindex of 26, co-authored 48 publications receiving 2026 citations. Previous affiliations of Michael Weig include University of Würzburg.
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Journal ArticleDOI
Adhesins in Human Fungal Pathogens: Glue with Plenty of Stick
TL;DR: Recent progress made in the field of adhesins in human fungal pathogens is summarized and the importance of these proteins in establishment of fungal diseases is underscored.
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Improved clinical laboratory identification of human pathogenic yeasts by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
TL;DR: A significant advantage of MALDI-TOF MS over biochemistry in the recognition of isolates novel to the system was observed, and will substantially improve fungal diagnostics and patient treatment.
Journal ArticleDOI
The Cell Wall of the Human Pathogen Candida glabrata: Differential Incorporation of Novel Adhesin-Like Wall Proteins
Piet W. J. de Groot,Eefje A. Kraneveld,Qing Yuan Yin,Henk L. Dekker,Uwe Groß,Wim Crielaard,Chris G. de Koster,Oliver Bader,Frans M. Klis,Michael Weig +9 more
TL;DR: It is proposed that the large repertoire of adhesin(-like) genes of C. glabrata contributes to its adaptability and virulence and is reflected in alterations in adhesion capacity and cell surface hydrophobicity.
Journal ArticleDOI
Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans
Claire M. Martel,Josie E. Parker,Oliver Bader,Michael Weig,Uwe Gross,Andrew G. S. Warrilow,Nicola J. Rolley,Diane E. Kelly,Steven L. Kelly +8 more
TL;DR: The results suggest that missense mutations in ERG3 might arise in C. albicans more frequently than currently supposed and that the clinical significance of erg3 mutants, including those in which additional mechanisms also contribute to resistance, should not be discounted.
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A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B
Claire M. Martel,Josie E. Parker,Oliver Bader,Michael Weig,Uwe Gross,Andrew G. S. Warrilow,Diane E. Kelly,Steven L. Kelly +7 more
TL;DR: A clinical isolate of Candida albicans was identified as an erg5 (encoding sterol C22 desaturase) mutant in which ergosterol was not detectable and ergosta 5,7-dienol comprised > 80% of the total sterol fraction as discussed by the authors.