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Michel Manfait

Researcher at Centre national de la recherche scientifique

Publications -  83
Citations -  2126

Michel Manfait is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Raman spectroscopy & Intracellular. The author has an hindex of 24, co-authored 83 publications receiving 1981 citations. Previous affiliations of Michel Manfait include University of Reims Champagne-Ardenne & Institut national de la recherche agronomique.

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Embolization of hepatocellular carcinoma with drug-eluting beads: Doxorubicin tissue concentration and distribution in patient liver explants

TL;DR: Doxorubicin-eluting beads provide a sustained delivery of drug for a period of 1 month and local tissue concentrations above cytotoxic threshold in HCC-bearing livers and compare it with histologic modifications.
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Combination of FTIR spectral imaging and chemometrics for tumour detection from paraffin-embedded biopsies

TL;DR: FTIR spectral imaging was applied on formalin-fixed paraffin-embedded biopsies from colon and skin cancerous lesions and tumour areas were successfully demarcated from the rest of the tissue in both Colon and skin independently of the embedding material and of the substrate.
Journal Article

Inhibition of growth and induction of differentiation of promyelocytic leukemia (HL-60) by carotenoids from Crocus sativus L.

TL;DR: The seminatural (DMCRT and CRT) and natural carotenoids (CRCs) of Crocus sativus L. are not provitamin A precursors and could therefore be less toxic than retinoids, even at high doses.
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Discriminating nevus and melanoma on paraffin-embedded skin biopsies using FTIR microspectroscopy.

TL;DR: The main objective of this in vitro study was to demonstrate the applicability of infrared spectral imaging to separate, on paraffinised biopsies, pigmented nevi (benign skin lesions) from melanomas (malignant skin lesions).
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Spatial distribution of protein and phenolic constituents in wheat grain as probed by confocal Raman microspectroscopy

TL;DR: In this article, the protein content and composition of the starchy endosperm and the composition of aleurone cells walls in arabinoxylan and ferulic acid derivatives were investigated.