M
Michela Gallagher
Researcher at Johns Hopkins University
Publications - 297
Citations - 33385
Michela Gallagher is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Hippocampal formation & Hippocampus. The author has an hindex of 95, co-authored 293 publications receiving 31710 citations. Previous affiliations of Michela Gallagher include University of Vermont & Texas A&M University.
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Spatial learning in male and female Long-Evans rats.
TL;DR: It is suggested that the age at which rats are assessed may be an important factor, possibly reflecting a different course in the relatively protracted maturation of the hippocampus in male and female rats.
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Teaching old rats new tricks: age-related impairments in olfactory reversal learning
TL;DR: The data indicate that rats show independent decline of different brain systems during normal aging and suggest orbitofrontal cortex as one prefrontal area where changes may be localized for further study.
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Cognitive decline associated with normal aging in rats: a neuropsychological approach
TL;DR: Although correlations between scores on the two tasks for individual aged rats were not reliable, only those aged rats that performed outside the performance range of young rats in the water maze were impaired on acquisition of the recognition memory task, suggesting that these brain regions may deteriorate in the same subgroup of aged rats.
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The basolateral complex of the amygdala is necessary for acquisition but not expression of CS motivational value in appetitive Pavlovian second-order conditioning.
TL;DR: The results show that although the ABL is critical for second‐order conditioning, this role is limited to acquisition of information about the motivational value of the first‐order CS, and it is not critical for maintenance of this information or for its use in forming second‐ order associations.
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GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus
Katherine A. Helm,Rebecca P. Haberman,S. L. Dean,Eileen C. Hoyt,Thorsten Melcher,Pauline K. Lund,Michela Gallagher +6 more
TL;DR: Evidence is provided that GABAB receptor antagonists may provide a pharmacological therapy for cognitive impairment, sharing mechanistic features with genetic approaches to reduce CREB2 activity and to augment long-term memory.