M
Michele A. Pellegrino
Researcher at Scripps Health
Publications - 96
Citations - 2989
Michele A. Pellegrino is an academic researcher from Scripps Health. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 31, co-authored 96 publications receiving 2980 citations.
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Journal ArticleDOI
Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethylisothiouronium bromide.
TL;DR: In vitro treatment of sheep red blood cells with the sulfhydryl compound 2-aminoethylisothiouronium bromide under suitable experimental conditions greatly enhances their ability to form rosettes with human lymphoid cells.
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Salt extraction of soluble HL-A antigens.
TL;DR: Application of the hypertonic salt extraction method is now yielding sufficient HL-A antigen to begin the elucidation of the molecular basis of transplantation individuality.
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Isolation of human T and B lymphocytes by rosette formation with 2-aminoethylisothiouronium bromide (AET) — Treated sheep red blood cells and with monkey red blood cells
TL;DR: Purified human B and T lymphocytes were obtained by rosetting HPL with AET-SRBC or MRBC and separating the non-rosetted from the rosetted cells on Ficoll-Hypaque gradient.
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Characterization of WiDr: A Human Colon Carcinoma Cell Line
Philip D. Noguchi,Roslyn E. Wallace,Jessica L. Johnson,E. M. Earley,Stephen J. O'Brien,Soldano Ferrone,Michele A. Pellegrino,J. Milstien,C. Needy,W. Browne,John C. Petricciani +10 more
TL;DR: The establishment and characterization of WiDr is described, a cell line derived from a human colon carcinoma that produces carcinoembryonic antigen in culture, and has a doubling time of 15 hr with plating efficiency of 51%.
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Heterogeneous distribution of the determinants defined by monoclonal antibodies on HLA-A and B antigens bearing molecules.
TL;DR: Assays indicate that the determinants recognized by each monoclonal antibody is spatially close to the conventional serologically defined allotypic determinants only on some of the HLA-A and B allospecificities tested, and that sera with the same specificity may recognize different determinants on a given HLA/B alloantigen.