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Michele Dambrosio

Researcher at University of Foggia

Publications -  56
Citations -  1590

Michele Dambrosio is an academic researcher from University of Foggia. The author has contributed to research in topics: Positive end-expiratory pressure & Levobupivacaine. The author has an hindex of 19, co-authored 56 publications receiving 1447 citations. Previous affiliations of Michele Dambrosio include University of Bari.

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Impact of prolonged assisted ventilation on diaphragmatic efficiency: NAVA versus PSV

TL;DR: After prolonged controlled mechanical ventilation, neurally adjusted ventilator assist improves diaphragm efficiency whereas pressure support ventilation does not.
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Effects of Positive End-expiratory Pressure and Different Tidal Volumes on Alveolar Recruitment and Hyperinflation

TL;DR: The morphologic effect of positive end-expiratory pressure and of two tidal volumes were studied by computed tomography to determine whether setting the tidal volume at the upper inflection point of the pressure-volume curve of the respiratory system or 10 ml/kg hav should be set.
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Effects of recruitment maneuver and positive end-expiratory pressure on respiratory mechanics and transpulmonary pressure during laparoscopic surgery.

TL;DR: In patients submitted to laparoscopic surgery in Trendelenburg position, an open lung strategy applied after pneumoperitoneum induction increased transpulmonary pressure and led to alveolar recruitment and improvement of Ecw and gas exchange.
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Use of N-terminal pro-brain natriuretic peptide to detect acute cardiac dysfunction during weaning failure in difficult-to-wean patients with chronic obstructive pulmonary disease.

TL;DR: Serial measurements of NT‐proBNP plasma levels provided a noninvasive manner to detect acute cardiac dysfunction during an unsuccessful weaning trial in difficult to wean patients with chronic obstructive pulmonary disease.
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Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures.

TL;DR: High resolution oxymetry revealed a dual dose- and time-dependent effect of bupivacaine consisting of uncoupling of the mt Delta mu(H+)-controlled respiratory rates in a cyclosporine A-insensitive manner and further inhibition of the respiratory rates.