M
Michelene Hearth-Holmes
Researcher at University of Nebraska Medical Center
Publications - 17
Citations - 2129
Michelene Hearth-Holmes is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Lupus erythematosus & Population. The author has an hindex of 9, co-authored 15 publications receiving 1928 citations. Previous affiliations of Michelene Hearth-Holmes include Louisiana State University in Shreveport.
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Journal ArticleDOI
Combined Oral Contraceptives in Women with Systemic Lupus Erythematosus
Michelle Petri,Mimi Y. Kim,Kenneth C. Kalunian,Jennifer M. Grossman,Bevra H. Hahn,Lisa R. Sammaritano,Michael D. Lockshin,Joan T. Merrill,H. Michael Belmont,Anca Askanase,W. Joseph McCune,Michelene Hearth-Holmes,Mary Anne Dooley,Joan M. Von Feldt,Alan Friedman,Mark Tan,John A. Davis,Cronin Me,Betty Diamond,Meggan Mackay,Lisa Sigler,Michael Fillius,Ann Rupel,Frederick Licciardi,Jill P. Buyon +24 more
TL;DR: It is indicated that oral contraceptives do not increase the risk of flare among women with systemic lupus erythematosus whose disease is stable.
Journal ArticleDOI
The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: A randomized trial
Jill P. Buyon,Michelle Petri,Mimi Y. Kim,Kenneth C. Kalunian,Jennifer M. Grossman,Bevra H. Hahn,Joan T. Merrill,Lisa R. Sammaritano,Michael D. Lockshin,Graciela S. Alarcón,Susan Manzi,H. Michael Belmont,Anca Askanase,Lisa Sigler,Mary Anne Dooley,Joan M. Von Feldt,W. Joseph McCune,Alan Friedman,Jane Wachs,Cronin Me,Michelene Hearth-Holmes,Mark Tan,Frederick Licciardi +22 more
TL;DR: This multicenter, double-blind trial found no significant difference in flare rate between HRT and placebo groups, and health issues specific to women warrant attention and need to be confronted in patients with SLE.
Journal ArticleDOI
Combined oral contraceptives in women with systemic lupus erythematosus
Michelle Petri,Mimi Y. Kim,Kenneth C. Kalunian,Jennifer M. Grossman,Bevra H. Hahn,Lisa R. Sammaritano,Michael D. Lockshin,Joan T. Merrill,H. Michael Belmont,Anca Askanase,W. Joseph McCune,Michelene Hearth-Holmes,Mary Anne Dooley,Joan M. Von Feldt,Alan Friedman,Mark Tan,John A. Davis,Cronin Me,Betty Diamond,Meggan Mackay,Lisa Sigler,Michael Fillius,Ann Rupel,Frederick Licciardi,Jill P. Buyon +24 more
TL;DR: This study indicates that oral contraceptives do not increase the risk of flare among women with systemic lupus erythematosus whose disease is stable and is within the prespecified 9 percent margin for noninferiority.
Journal Article
Literacy in patients with a chronic disease: systemic lupus erythematosus and the reading level of patient education materials.
Michelene Hearth-Holmes,Peggy Murphy,Terry C. Davis,Indrani Nandy,Celeste G. Elder,Louise H. Broadwell,Robert E. Wolf +6 more
TL;DR: Assessment of literacy in a sample of patients with systemic lupus erythematosus revealed that race and education correlated with reading, but age, sex, and SES did not, and the readability of surveyed SLE patient education materials ranged from 7th-15th grade level.
Journal ArticleDOI
Celastrol Inhibits Inflammatory Stimuli-Induced Neutrophil Extracellular Trap Formation
Yangsheng Yu,C. D. Koehn,Yinshi Yue,Song Li,Geoffrey M. Thiele,Michelene Hearth-Holmes,Ted R. Mikuls,James R. O'Dell,Lynell Warren Klassen,Z. Zhang,Kaihong Su +10 more
TL;DR: The data reveals that celastrol potently inhibits neutrophil oxidative burst and NET formation induced by different inflammatory stimuli, possibly through downregulating the SYK-MEK-ERK-NFκB signaling cascade.