M
Miguel Ángel Martínez
Researcher at National Autonomous University of Mexico
Publications - 15
Citations - 699
Miguel Ángel Martínez is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Ionic liquid & Mercury (element). The author has an hindex of 6, co-authored 15 publications receiving 613 citations. Previous affiliations of Miguel Ángel Martínez include Ensenada Center for Scientific Research and Higher Education.
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Journal ArticleDOI
A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples
Samia N. Naccache,Scot Federman,Narayanan Veeraraghavan,Matei Zaharia,Deanna Lee,Erik Samayoa,Jerome Bouquet,Alexander L. Greninger,Ka Cheung Luk,Barryett Enge,Debra A. Wadford,Sharon Messenger,Gillian Genrich,Kristen Pellegrino,Gilda Grard,Eric M. Leroy,Bradley S. Schneider,Joseph N. Fair,Miguel Ángel Martínez,Pavel Isa,John A. Crump,Joseph L. DeRisi,Taylor Sittler,John Hackett,Steve Miller,Charles Y. Chiu +25 more
TL;DR: SURPI is described, a computational pipeline for pathogen identification from complex metagenomic NGS data generated from clinical samples, and use of the pipeline is demonstrated in the analysis of 237 clinical samples comprising more than 1.1 billion sequences.
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Discovery of a novel polyomavirus in acute diarrheal samples from children.
Guixia Yu,Alexander L. Greninger,Pavel Isa,Tung Gia Phan,Miguel Ángel Martínez,Maria de la Luz Sanchez,Juan F. Contreras,José Ignacio Santos-Preciado,Julie Parsonnet,Steve Miller,Joseph L. DeRisi,Eric Delwart,Carlos F. Arias,Charles Y. Chiu +13 more
TL;DR: A multiple sequence alignment revealed thatMXPyV is a closely related variant of the recently reported MWPyV and HPyV10 polyomaviruses, and further studies will be important to determine the association, if any, of MXPyV with disease in humans.
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Gangliosides Have a Functional Role during Rotavirus Cell Entry
TL;DR: It is suggested that rotaviruses can attach to cell surface in the absence of gangliosides but require them for productive cell entry, confirming their functional role during rotavirus cell entry.
Journal ArticleDOI
DNA Microarray for Detection of Gastrointestinal Viruses
Miguel Ángel Martínez,María de los Dolores Soto-del Río,Rosa María Gutiérrez,Charles Y. Chiu,Alexander L. Greninger,Juan F. Contreras,Susana López,Carlos F. Arias,Pavel Isa +8 more
TL;DR: The microarray showed good performance for detection of RV-A, HAstV, and calicivirus, while the sensitivity for HAdV and HEV was low, and some discrepancies in detection of mixed infections were observed and were addressed by reverse transcription-quantitative PCR of the viruses involved.
Journal ArticleDOI
Malaria Hidden in a Patient with Diffuse Large-B-Cell Lymphoma and Sickle-Cell Trait
María Linares,Enriqueta Albizua,Darío Méndez,José M. Rubio,Alejandra Martínez-Serna,Miguel Ángel Martínez,Efren Salto,Antonio Puyet,Amalia Diez,Joaquin Martinez-Lopez,José M. Bautista +10 more
TL;DR: An African patient with sickle cell trait who was diagnosed in Spain with B-cell lymphoma and undergoing chemotherapy and autologous stem cell transplantation suggests that the humoral response and parasite removal by the spleen may afford protection from overt disease and even help maintain subclinical human reservoirs of the disease.