Debra A. Wadford

TL;DR: The CRISPR-based DETECTR assay provides a visual and faster alternative to the US Centers for Disease Control and Prevention SARS-CoV-2 real-time RT–PCR assay, with 95% positive predictive agreement and 100% negative predictive agreement.

TL;DR: SURPI is described, a computational pipeline for pathogen identification from complex metagenomic NGS data generated from clinical samples, and use of the pipeline is demonstrated in the analysis of 237 clinical samples comprising more than 1.1 billion sequences.

TL;DR: In this article, the authors identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples from 44 counties in California, a state in the western United States.

TL;DR: Findings strengthen the putative association between enterovirus D68 and acute flaccid myelitis and the contention that acute Flaccid Myelitis is a rare yet severe clinical manifestation of enterov virus D68 infection in susceptible hosts.

TL;DR: The genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020 is investigated, using samples from 36 patients spanning nine counties and the Grand Princess cruise ship to support contact tracing, social distancing, and travel restrictions to contain the spread of the virus.