M
Mika Kakimoto
Researcher at Kobe University
Publications - 1
Citations - 1009
Mika Kakimoto is an academic researcher from Kobe University. The author has contributed to research in topics: Cas9 & Genome editing. The author has an hindex of 1, co-authored 1 publications receiving 731 citations.
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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
Keiji Nishida,Takayuki Arazoe,Nozomu Yachie,Nozomu Yachie,Nozomu Yachie,Satomi Banno,Mika Kakimoto,Mayura Tabata,Masao Mochizuki,Aya Miyabe,Michihiro Araki,Kiyotaka Y. Hara,Zenpei Shimatani,Akihiko Kondo +13 more
TL;DR: The toxicity associated with the nuclease-based CRISPR/Cas9 system was greatly reduced in the Target-AID complexes, and it was demonstrated that off-target effects were comparable to those of conventional CRISpr/Cas systems, with a reduced risk of indel formation.