M
Milo J. Aukerman
Researcher at University of California, San Diego
Publications - 7
Citations - 1028
Milo J. Aukerman is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Gene & Leucine zipper. The author has an hindex of 7, co-authored 7 publications receiving 1005 citations.
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Journal ArticleDOI
Maize regulatory gene opaque-2 encodes a protein with a "leucine-zipper" motif that binds to zein DNA
TL;DR: The opaque-2 locus (o2) in maize regulates the expression of many members of the zein multigene family of storage proteins as mentioned in this paper, and the presumptive amino acid sequence of the protein (O2) specified by the O2 cDNA contains a "leucine-zipper" domain characteristic of some mammalian and fungal transcription activation factors.
Journal ArticleDOI
Opaque-2 is a transcriptional activator that recognizes a specific target site in 22-kD zein genes.
TL;DR: The binding site for the O2 protein (O2) in the promoter of 22-kD zein genes is identified and a likely explanation at the molecular level for the differential effect of o2 mutations on expression of certain members of the zein gene family is suggested.
Journal ArticleDOI
OHP1: a maize basic domain/leucine zipper protein that interacts with opaque2.
TL;DR: Models to accommodate OHP1 in the regulation of zein gene expression by O2 are proposed and previously reported data are proposed.
Journal ArticleDOI
An arginine to lysine substitution in the bZIP domain of an opaque-2 mutant in maize abolishes specific DNA binding.
TL;DR: The correlation between this mutation in o2 and the altered pattern of zein expression strongly suggests that O2 regulates transcription of certain members of the zein multigene family through direct interaction with theZein promoters and not through the transcriptional activation of some other regulator ofZein gene expression.
Book ChapterDOI
Regulation of α-Zein Gene Expression During Maize Endosperm Development
TL;DR: Investigation into the mechanisms responsible for the coordinated regulation of the zein multigene family may provide insight into the general regulatory strategies employed by higher organisms with regard to multigenes families.