M
Min-Shu Zeng
Researcher at Sichuan Agricultural University
Publications - 8
Citations - 142
Min-Shu Zeng is an academic researcher from Sichuan Agricultural University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 1, co-authored 1 publications receiving 106 citations.
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Journal ArticleDOI
A high-selenium diet induces insulin resistance in gestating rats and their offspring.
Min-Shu Zeng,Xi Li,Yan Liu,Hua Zhao,Ji-Chang Zhou,Ke Li,Jia-Qiang Huang,Lv-Hui Sun,Jiayong Tang,Xinjie Xia,Xinjie Xia,Kang-Ning Wang,Xin Gen Lei,Xin Gen Lei +13 more
TL;DR: Supranutrition of Se as a Se-enriched yeast in rats induced gestational diabetes and insulin resistance and expression of six selenoprotein genes, in particular Gpx1, was linked to this metabolic disorder.
Journal ArticleDOI
Anti-lung cancer effect of paclitaxel solid lipid nanoparticles delivery system with curcumin as co-loading partner in vitro and in vivo
Chao Pi,Wenmei Zhao,Min-Shu Zeng,Jiyuan Yuan,Hongping Shen,Ke Li,Zhilian Su,Zerong Liu,Jie Wen,Xinjie Song,Robert J. Lee,Yumeng Wei,Ling Zhao +12 more
TL;DR: PC-SLNs can greatly reduce the dose of PTX while still achieving the same therapeutic effect on four cancer cell lines, among which the inhibitory effect on A549 lung cancer cells was the strongest.
Journal ArticleDOI
Formulation of the novel structure curcumin derivative–loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in vitro
Ke Li,Chao Pi,Jie Wen,Yingmeng He,Jiyuan Yuan,Hongping Shen,Wenmei Zhao,Min-Shu Zeng,Xinjie Song,Robert J. Lee,Yumeng Wei,Ling Zhao +11 more
TL;DR: CU1 retained the inhibitory effect of CU against tumor cells, while improving stability and safety, and CU1-SLN presents a promising strategy for the treatment of liver and lung cancer.
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Novel Curcumin Derivative-Decorated Ultralong-Circulating Paclitaxel Nanoparticles: A Novel Delivery System with Superior Anticancer Efficacy and Safety
Yumeng Wei,Min-Shu Zeng,Chao Pi,Hongping Shen,Jiyuan Yuan,Ying Zuo,Jie Wen,Pu Guo,Wenmei Zhao,Ke Li,Zhilian Su,Xinjie Song,ShaoZhi Fu,Robert J. Lee,Ling Zhao +14 more
TL;DR: In this paper , a self-developed curcumin derivative (CUD) was chosen as the carrier to develop a long-acting PTX nano-delivery system (PTX-Sln@CUD), in order to improve its pharmacokinetic behavior, anti-breast cancer efficacy and safety.
Journal ArticleDOI
The Effects of a Novel Curcumin Derivative Loaded Long-Circulating Solid Lipid Nanoparticle on the MHCC-97H Liver Cancer Cells and Pharmacokinetic Behavior
Yumeng Wei,Ke Li,Wenmei Zhao,Yingmeng He,Hongping Shen,Jiyuan Yuan,Chao Pi,Xiaomei Zhang,Min-Shu Zeng,ShaoZhi Fu,Xinjie Song,Robert J. Lee,Ling Zhao +12 more
TL;DR: In vivo, CU1-LSLN prolonged the retention time of the drug, the area under the curve (AUC) increased significantly, and no significant liver toxicity was observed, indicating that CU1 was well encapsulated by LSLN and existed in amorphous form.