Min Suk Yang

TL;DR: Chalcones 1-20, a new class of glycosidase inhibitors, were synthesized, and their glycoside inhibitory activities were investigated as discussed by the authors, showing that sulfonamide chalconses 17-20 had more potent alpha-glucosidase inhibitory activity than aminated chalcone 13-16.

TL;DR: It is proved that the pterocarpan skeleton is a new class of lead structure for neuraminidase inhibitors, and the most potent pterOCarpan-derived inhibitor 1 may bind to another binding pocket adjacent to the active site.

TL;DR: Six 1,3-diphenylpropanes exhibiting inhibitory activities against both the monophenolase and diphenolases actions of tyrosinase were isolated from the methanol extract of Broussonetia kazinoki and fully spectroscopically characterized.

TL;DR: The most potent K+ channel blocker was the 3'-(p-aminobenzene-sulfonylhydroxy)-4-hydroxychalcone 17, in which the sulfonyloxy group is placed on the A-ring.

TL;DR: Six diarylbutane lignans 1-5 and one aryltetralin lignan 6 were isolated from the methanol extracts of Myristica fragrans seeds and then 7-methyl ether diaryl butane lIGNan 4 has proven to be new a compound.