Ming-Fang He

TL;DR: This study identifies the high pretherapeutical serum IL-8 level in gastric cancer patients that was associated with poor response to platinum-based therapy, and it increased gradually during neoadjuvant chemotherapy and it decreased after radical surgery, and provides a novel strategy to improve the chemotherapeutical efficacy and the prognosis of Gastric cancer.

TL;DR: LC/MS/MS showed that the bioaccumulation in zebrafish embryos were increased in a time-dependent manner after 25 mg/L of 2,4-D treatment, and whole mount in situ hybridization confirmed the vmhc and amhc upregulation by 2, 4-Dtreatment.

TL;DR: The authors' zebrafish PDX (zPDX) model is a preclinically reliable in vivo model for GC and the zPDX model is also a promising platform for the translational research and personalized treatment on GC.

TL;DR: A novel mechanism underlying CAFs to promote tumor invasion during H. pylori infection is identified, which facilitates a better understanding of the molecular process of gastric carcinoma progression, and provides the potential strategies for gastric cancer therapy.

TL;DR: In this paper, the anti-angiogenic activity of Para-coumaric acid methyl ester (pCAME) was investigated on human umbilical vein endothelial cells (HUVECs) in vitro and zebrafish (Danio rerio) in vivo.