Ming-Xue Wu

TL;DR: A brief introduction to the applications of MOFs in controlled drug/cargo delivery and cancer therapy that have been reported in recent years is provided here.

TL;DR: Covalent organic frameworks (COFs) as discussed by the authors are a class of porous organic structures whose backbones were composed of light elements (B, C, N, O, Si) and linked by robust covalent bonds to endow such material with desirable properties, such as inherent porosity, well-defined pore aperture, ordered channel structure, large surface area, high stability, and multi-dimension.

TL;DR: Water-soluble carboxylatopillar[6]arene system achieved sustained drug release over 7 days due to stronger host-guest binding, suggesting that the nanovalve tightness further reinforces the desirable release of anticancer agent over a prolonged time at the lesion site.

TL;DR: A novel hydrazone covalent organic framework (COF) is designed and a polydopamine (PDA) method to immobilize COF on a stainless steel fiber for headspace solid-phase microextraction (HS-SPME) and the developed method was applied to the determination of pyrethroids in fruit and vegetable samples.

TL;DR: The present strategy offers not only the distinctly targeted drug delivery and release, but also excellent tumor inhibition efficacy of simultaneous chemophotothermal therapy, opening a new avenue for effective cancer treatment.