M
Mingkuan Lin
Researcher at George Mason University
Publications - 21
Citations - 798
Mingkuan Lin is an academic researcher from George Mason University. The author has contributed to research in topics: Working memory & Single-nucleotide polymorphism. The author has an hindex of 12, co-authored 21 publications receiving 674 citations. Previous affiliations of Mingkuan Lin include Krasnow Institute for Advanced Study & Inova Health System.
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Journal ArticleDOI
BDNF mediates improvements in executive function following a 1-year exercise intervention.
Regina L. Leckie,Lauren E. Oberlin,Michelle W. Voss,Ruchika Shaurya Prakash,Amanda N. Szabo-Reed,Laura Chaddock-Heyman,Siobhan M. Phillips,Neha P. Gothe,Emily L. Mailey,Victoria J. Vieira-Potter,Stephen A. Martin,Brandt D. Pence,Mingkuan Lin,Raja Parasuraman,Pamela M. Greenwood,Karl J. Fryxell,Jeffrey A. Woods,Edward McAuley,Arthur F. Kramer,Kirk I. Erickson +19 more
TL;DR: Results demonstrate that both age and BDNF serum levels are important factors to consider when investigating the mechanisms by which exercise interventions influence cognitive outcomes, particularly in elderly populations.
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Oxytocin receptor genetic variation promotes human trust behavior.
Frank Krueger,Raja Parasuraman,Vijeth Iyengar,Matthew P. Thornburg,Jaap Weel,Mingkuan Lin,Ellen Clarke,Kevin McCabe,Robert H. Lipsky +8 more
TL;DR: Genotyping of healthy male students and a trust game experiment show that a common occurring genetic variation in the OXTR gene is reliably associated with trust behavior rather than a general increase in trustworthy or risk behaviors.
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Identification and characterization of a G protein-binding cluster in α7 nicotinic acetylcholine receptors
TL;DR: It is demonstrated that direct coupling of α7 nAChRs to G proteins enables a downstream calcium signaling response that can persist beyond the expected time course of channel activation.
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Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory.
TL;DR: It is argued that reorienting attention to the target after invalid cues requires a phasic response, dependent on the nicotinic system, whereas orientating attention to valid cues requiresA tonic response; this shows synergistic effects within the human cholinergic system.
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Longitudinal change in working memory as a function of APOE genotype in midlife and old age.
TL;DR: A "cognitive phenotype" hypothesis arguing that the ε4 allele of the apolipoprotein E gene (APOE) is associated with lower efficiency of neuronal plasticity thereby resulting in poorer cognitive performance independently of the pathology of Alzheimer's disease is advanced.