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Miranda Chakos

Researcher at SUNY Downstate Medical Center

Publications -  44
Citations -  6065

Miranda Chakos is an academic researcher from SUNY Downstate Medical Center. The author has contributed to research in topics: Schizophrenia & Schizoaffective disorder. The author has an hindex of 26, co-authored 44 publications receiving 5857 citations. Previous affiliations of Miranda Chakos include Nathan Kline Institute for Psychiatric Research & University of North Carolina at Chapel Hill.

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Journal ArticleDOI

The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches

TL;DR: Because the clinical deterioration that occurs in schizophrenia may actually begin in the prepsychotic phase, early identification and intervention may favorably alter the course and outcome of schizophrenia.
Journal ArticleDOI

Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder

TL;DR: Patients with a history of suboptimal response to conventional treatments may show cognitive benefits from newer antipsychotic drugs, and there may be differences between atypical antipsychotics drugs in their patterns of cognitive effects.
Journal ArticleDOI

Longitudinal study of brain morphology in first episode schizophrenia

TL;DR: The finding of progressive ventricular enlargement in patients with poor outcome schizophrenia is consistent with the hypothesis that persistent positive and negative symptoms result in progressive brain changes in the form of ventricular enlargeement, possibly due to neurodegeneration rather than the confounding effects of treatment.
Book ChapterDOI

Valmet: A New Validation Tool for Assessing and Improving 3D Object Segmentation

TL;DR: Preliminary studies showed that the new tool could significantly improve intra- and inter-rater reliability of hippocampus segmentation to achieve intra-class correlation coefficients significantly higher than published elsewhere.