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Miriam Hatsue Honda Federico

Researcher at University of São Paulo

Publications -  31
Citations -  1147

Miriam Hatsue Honda Federico is an academic researcher from University of São Paulo. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cellular differentiation. The author has an hindex of 16, co-authored 31 publications receiving 1072 citations.

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Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study

TL;DR: LLL therapy was not effective in reducing severe oral mucositis, although a marginal benefit could not be excluded and it reduced RT interruptions in these head-and-neck cancer patients, which might translate into improved CRT efficacy.
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High-dose cisplatin concurrent to conventionally delivered radiotherapy is associated with unacceptable toxicity in unresectable, non-metastatic stage IV head and neck squamous cell carcinoma.

TL;DR: This concurrent CRT regimen is hardly delivered in stage IV, unresectable, locally advanced HNSCC pts, due to treatment-related toxicities and longer RT duration, as a subset of pts may benefit from this regimen.
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Efficacy of low-level laser therapy and aluminum hydroxide in patients with chemotherapy and radiotherapy-induced oral mucositis.

TL;DR: The prophylactic use of both treatments proposed in this study seems to reduce the incidence of severe OM lesions, however, the LLLT was more effective in delaying the appearance of severeOM.