M
Mirosław Zarębski
Researcher at Jagiellonian University
Publications - 31
Citations - 1432
Mirosław Zarębski is an academic researcher from Jagiellonian University. The author has contributed to research in topics: DNA damage & DNA. The author has an hindex of 13, co-authored 31 publications receiving 1231 citations.
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Journal ArticleDOI
A Potential New Pathway for Staphylococcus aureus Dissemination: The Silent Survival of S. aureus Phagocytosed by Human Monocyte-Derived Macrophages
Malgorzata Kubica,Krzysztof Guzik,Joanna Koziel,Mirosław Zarębski,Walter Richter,Barbara Gajkowska,Anna Golda,Agnieszka Maciag-Gudowska,Klaudia Brix,Les Shaw,Timothy J. Foster,Jan Potempa +11 more
TL;DR: The data indicate that the ability of S. aureus to survive phagocytosis by macrophages is determined by multiple virulence factors in a way that differs considerably from its interactions with other cell types.
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Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells
TL;DR: It is shown that the ACE2 protein is required for viral entry but that it is not the primary binding site on the cell surface, and heparan sulfate proteoglycans function as adhesion molecules, increasing the virus density on cell surface and possibly facilitating the interaction between HCoV-NL63 and its receptor.
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Entry of Human Coronavirus NL63 into the Cell
Aleksandra Milewska,Paulina Nowak,Katarzyna Owczarek,Artur Szczepanski,Mirosław Zarębski,Agnieszka Hoang,Krzysztof Berniak,Jacek Wojarski,Slawomir Zeglen,Zbigniew Baster,Zenon Rajfur,Krzysztof Pyrc +11 more
TL;DR: This study mapped the process of HCoV-NL63 entry into the LLC-Mk2 cell line and ex vivo three-dimensional tracheobronchial tissue using the most advanced 3D tissue culture system mimicking the epithelium of conductive airways to allow for a better understanding of the infection process.
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Minimizing photobleaching during confocal microscopy of fluorescent probes bound to chromatin: role of anoxia and photon flux.
TL;DR: The aim of this work was to investigate the role of oxygen in the photobleaching of fluorophores bound to DNA in fixed cells, and to explore whether anoxia could minimize such bleaching.
Journal ArticleDOI
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes.
Hong Zhao,Toshiki Tanaka,Toshiki Tanaka,H. Dorota Halicka,Frank Traganos,Mirosław Zarębski,Jurek Dobrucki,Zbigniew Darzynkiewicz +7 more
TL;DR: Cytometric analysis of CHP and CAA provides the means to measure the effectiveness of exogenous factors, which either through lowering aerobic metabolism or neutralizing radicals may protect DNA from such damage.