Mogens Christensen

TL;DR: A new peptide with both adipokinetic activity in the locust and red pigment-concentratingActivity in the shrimp, can be readily separated from the adipokinetics hormone in extracts of corpora cardiaca (CC) from Schistocerca americana gregaria by the use of gel chromatography and the Leander adspersus bioassay.

TL;DR: The complete identity in purification behavior, in amino acid composition, in electrophoresis, and in partition chromatography with the previously purified red pigment-concentrating hormone from the prawn Pandalus borealis, strongly indicate structural identity between the hormones of the two species.

TL;DR: RPCH and a number of analogues that differ only in the C-terminal part of the hormone, have been synthesized and assayed for biological activity on the shrimp Leander adspersus and it has been shown that the indole skeleton of tryptophan is an absolute requirement for the biological activity of the hormones.

TL;DR: Red pigment concentrating hormone-like activity (RPCA) was found in all post-embryonic life cycle stages of S. gregaria, and seems to be present in equal quantities in both males and females.

TL;DR: Assay of the biological activity of the various synthetic compounds in the shrimp Leander adspersus has established that only the C-terminal tryptophan residue is indispensable for the blanching effect of the hormone, although elongation of the chain length improves its potency.