Mohamed T. Abdel Aziz

TL;DR: Administration of MSCs in chemically induced HCC has tumor suppressive effects as evidenced by down regulation of Wnt signaling target genes concerned with antiapoptosis, mitogenesis, cell proliferation and cell cycle regulation, with subsequent amelioration of liver histopathological picture and liver function.

TL;DR: MSC therapy significantly improved 24 h urinary albumin, serum urea and creatinine concentrations, increased angiogenic growth factor VEGF, and anti-apoptotic protein bcl2 while decreased the pro-inflammatory TNF-α, fibrogenic growth factor TGF β, and pro-apopotic protein Bax.

TL;DR: The novel water soluble curcumin derivative by its small dose possesses antidiabetic actions and that heme oxygenase induction seems to play an important role in its anti-diabetic effects.

TL;DR: Rat bone marrow harbors cells that have the capacity to differentiate into functional insulin-producing cells capable of controlling blood glucose level in diabetic rats that may provide a source of cell-based therapy for DM.

TL;DR: NCD andCurcumin prevented diabetes-induced upregulation of these parameters and improved left ventricular function and the effect of the NCD was better than the same dose of curcumin.