M
Mohammed H. Al-Qahtani
Researcher at King Abdulaziz University
Publications - 158
Citations - 3365
Mohammed H. Al-Qahtani is an academic researcher from King Abdulaziz University. The author has contributed to research in topics: Population & Cancer. The author has an hindex of 28, co-authored 149 publications receiving 2681 citations.
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Journal ArticleDOI
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies
TL;DR: Key aspects of telomerase assembly, intracellular trafficking and recruitment to telomeres for completing DNA synthesis, which may provide novel targets for the development of anticancer agents are revealed.
Journal Article
Expression of Matrix Metalloproteinases (MMPs) in Primary Human Breast Cancer: MMP-9 as a Potential Biomarker for Cancer Invasion and Metastasis
Adnan Merdad,Sajjad Karim,Hans-Juergen Schulten,Ashraf Dallol,Abdelbaset Buhmeida,Fatima Al-Thubaity,Mamdooh Gari,Adeel G. Chaudhary,Adel M. Abuzenadah,Mohammed H. Al-Qahtani +9 more
TL;DR: Gene expression signatures are unique for specific grades and Overexpression of MMPs in higher grades might be associated with BC tumor invasion and metastasis, and MMP-9 is suggested to be of limited prognostic value.
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Specific nutrient combination effects on tax, NF-κB and MMP-9 in human T-cell lymphotropic virus -1 positive malignant T-lymphocytes
Steve Harakeh,Rania Azar,Esam I. Azhar,Ghazi A. Damanhouri,Mourad Assidi,Muhammad Abu-Elmagd,Muhammad Abu-Elmagd,Mohammed H. Al-Qahtani,Taha A. Kumosani,Aleksandra Niedzwiecki,Matthias Rath,Ahmed M. Al-Hejin,Elie K. Barbour,Elie K. Barbour,Mona Diab-Assaf +14 more
TL;DR: The results of this study indicate that a specific nutrient synergy targeted multiple levels pertinent to the progression of ATL, its activity was mediated through the NF-κB pathway, and hence has the potential to be integrated in the treatment of this disease as a natural potent anticancer agent.
Journal ArticleDOI
Role of gut microbiota in obesity, type 2 diabetes and Alzheimer's disease
Muhammad Imran Naseer,Fehmida Bibi,Mohammed H. Al-Qahtani,Adeel G. Chaudhary,Esam I. Azhar,Mohammad Amjad Kamal,Muhammad Yasir +6 more
TL;DR: The aim of this review is to discuss the current findings that may explain the cascade of gut microbial flora participation in the development of obesity, T2DM and further initiation of AD.
Journal ArticleDOI
Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention.
TL;DR: An in-depth understanding of role of miRNAs in the metastatic cascade may lead to the identification of novel targets for anti-metastatic therapeutics as well as potential candidatemiRNAs for cancer treatment.