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Esam I. Azhar

Researcher at King Abdulaziz University

Publications -  312
Citations -  10197

Esam I. Azhar is an academic researcher from King Abdulaziz University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 38, co-authored 251 publications receiving 7773 citations.

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Coronaviruses - drug discovery and therapeutic options.

TL;DR: The epidemiology, virology, clinical features and current treatment strategies of SARS and MERS are summarized, and the discovery and development of new virus-based and host-based therapeutic options for CoV infections are discussed.
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Evidence for camel-to-human transmission of MERS coronavirus

TL;DR: The isolation and sequencing of Middle East respiratory syndrome coronavirus obtained from a dromedary camel and from a patient who died of laboratory-confirmed MERS-CoV infection after close contact with camels that had rhinorrhea suggest that this fatal case of human MSPV infection was transmitted throughclose contact with an infected camel.
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Reducing mortality from 2019-nCoV: host-directed therapies should be an option.

TL;DR: The timing of interferon treatment in patients with sepsis, resulting in increased survival, is studied and expansion of anti-2019nCoV-specific T cells, as cellular drugs, could aid to prepare T-cell products for the adjunct treatment of patients with severe 2019-n coV infection.
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Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission

TL;DR: A comprehensive update and synthesis of the latest available data on the epidemiology, determinants, and risk factors of primary, household, and nosocomial transmission of MERS-CoV are provided, and measures to reduce risk of transmission are suggested.