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Mohd. Aqil

Researcher at Jamia Hamdard

Publications -  188
Citations -  5549

Mohd. Aqil is an academic researcher from Jamia Hamdard. The author has contributed to research in topics: Transdermal & Chemistry. The author has an hindex of 33, co-authored 149 publications receiving 4252 citations. Previous affiliations of Mohd. Aqil include Hamdard University.

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Evaluation of Carbopol-Methyl Cellulose Based Sustained-Release Ocular Delivery System for Pefloxacin Mesylate Using Rabbit Eye Model

TL;DR: The results demonstrated that the carbopol/methyl cellulose mixture can be used as an in situ gelling vehicle to enhance the ocular bioavailability of pefloxacin mesylate.
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Development of clove oil based nanoemulsion of olmesartan for transdermal delivery: Box–Behnken design optimization and pharmacokinetic evaluation

TL;DR: A transdermal nanoemulsion formulation of olmesartan using Box-Behnken design and to evaluate it for pharmacokinetic study was developed and optimized in this paper, where the optimized formulation has presented the particle size of 53.11 ± 3.13 µm, polydispersity index 0.335 − 0.008 and transtermal flux 12.65 − 1.60 µm 2 /h.
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Part I: Development and optimization of solid-lipid nanoparticles using Box-Behnken statistical design for ocular delivery of gatifloxacin.

TL;DR: This study aims to improve gatifloxacin bioavailability to the eye using solid-lipid nanoparticles (SLN) by optimizing formulations by three-factor, three-level Box-Behnken statistical design and in vitro release data were fitted to release kinetics equations.
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Design, formulation and optimization of valsartan transdermal gel containing iso-eucalyptol as novel permeation enhancer: preclinical assessment of pharmacokinetics in Wistar albino rats.

TL;DR: It was concluded that the developed transdermal gel accentuates the flux of valsartan and could be used as an antihypertensive dosage form for effectivetransdermal delivery of valartan.
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Ultrasonically tailored, chemically engineered and "QbD" enabled fabrication of agomelatine nanoemulsion; optimization, characterization, ex-vivo permeation and stability study.

TL;DR: The higher drug permeation profile of optimized Ago-NE confirmed that the solubility of agomelatine has been improved and was found to be 90% and 40% respectively.