Monica Rapino

TL;DR: Ageing myocardial cells disclose a suboptimal response, which underlines the possibility that they can become more sensitive to damaging factors or diseases, more frequently occurring during ageing, probably due to an exploited molecular control of apoptosis.

TL;DR: The different responses to hypoxic challenge during life show that the young seem the most reactive and damaged, as is well documented by p53-mediated HIF-1α stabilization, while increasing p66 expression and tyrosine phosphorylation provide evidence of longevity and oxidative stress resistance.

TL;DR: The results in the in vitro system suggest brain non-neuronal cells as a target in the treatment of oxidative conditions, whereas findings in the ex vivo system and docking analyses imply the potential roles of CBD and CBG as neuroprotective agents.

TL;DR: In this paper, the phenolic and terpenophenolic compounds were assayed in the water extract of the hemp variety Futura 75 and the results of phytochemical analysis suggested the cannabidiol, cannabbidiolic acid and rutin as the prominent phytocompounds.

TL;DR: The CBD modulates hypothalamic neuromodulators consistently with its anorexigenic role, whereas the CBG effect on the same mediators suggests alternative mechanisms, possibly involving peripheral pathways.