Monique Bassetti

TL;DR: The results suggest that patients with constitutively active adenylyl cyclase have hyperactive tumors; the sensitivity of these tumors to inhibitory agents (somatostatin and dopamine), possibly counteracting the expression of activating mutations, might explain the low rate of tumor growth.

TL;DR: A regulated secretory pathway characterized by the expression and stimulated exocytosis of a typical marker forregulated secretory granules, the presence of dense-core vesicles, and the ability to undergo [Ca2+] i increase upon specific stimuli is present in cultured hippocampal astrocytes.

TL;DR: The results support the idea that the frequency of mixed adenomas with mixed cells may be higher than that believed previously, and the simultaneous presence of two hormones in the same secretory granule could explain why, in patients having mixed tumors, factors able to stimulate or inhibit the release of one hormone can also stimulate or inhibits the secretion of the other.

TL;DR: Data indicate that in this patient serum TSH had an apparent mol wt smaller than that of normal TSH and an increased biological activity which, along with the autonomous TSH secretion, account for hyperthyroidism in the presence of lownormal TSH levels.

TL;DR: The results indicate that myristoylated reductase localizes to ER and mitochondria by different mechanisms, and reveal a novel role for myristic acid in protein targeting.