M
Morgane Bayle
Researcher at University of Montpellier
Publications - 6
Citations - 39
Morgane Bayle is an academic researcher from University of Montpellier. The author has contributed to research in topics: Chemistry & Ghrelin. The author has an hindex of 3, co-authored 4 publications receiving 30 citations.
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Journal ArticleDOI
Protection of pancreatic β-cell function by dietary polyphenols
Margherita Dall'Asta,Morgane Bayle,Jérémie Neasta,Francesca Scazzina,Renato Bruni,Gérard Cros,Daniele Del Rio,Daniele Del Rio,Catherine Oiry +8 more
TL;DR: Animal and in vitro studies selected in this review highlight the direct action of polyphenols on pancreatic β-cells, stimulating insulin secretion through the activation of specific cellular targets and protecting these cells from damages mediated by oxidative stress and inflammation, both typically elevated in diabetes.
Journal ArticleDOI
Development and validation of a liquid chromatography-electrospray ionization-tandem mass spectrometry method for the determination of urolithin C in rat plasma and its application to a pharmacokinetic study.
Morgane Bayle,Céline Roques,Bénédicte Marion,Michel Audran,Catherine Oiry,Françoise M.M. Bressolle-Gomeni,Gérard Cros +6 more
TL;DR: This highly specific and sensitive liquid chromatography-electrospray ionization-tandem mass spectrometry method for the determination of urolithin C in rat plasma was used to analyze samples collected during preclinical pharmacokinetic studies in rats.
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Urolithin C increases glucose-induced ERK activation which contributes to insulin secretion.
TL;DR: It is reported that urolithin C enhanced glucose‐induced extracellular signal‐regulated kinases 1/2 (ERK1/2) activation as shown by higher phosphorylation levels in INS‐1 β‐cells, indicating that the pharmacological action of urolithsin C on insulin secretion relies, in part, on its capacity to enhance glucose‐ induced ERK1 /2 activation.
Journal ArticleDOI
Liver-Expressed Antimicrobial Peptide 2 antagonizes the insulinostatic effect of ghrelin in rat isolated pancreatic islets.
Morgane Bayle,Sylvie Peraldi-Roux,Guillaume Gautheron,Gérard Cros,Catherine Oiry,Jérémie Neasta +5 more
TL;DR: In this paper, Liver-Expressed Antimicrobial Peptide 2 (LEAP2) was recognized as an endogenous G-protein coupled receptor (GPCR) ligand that blocks ghrelin-induced actions.
Journal ArticleDOI
Design and Characterization of a Triazole-Based Growth Hormone Secretagogue Receptor Modulator Inhibiting the Glucoregulatory and Feeding Actions of Ghrelin.
Sylvie Peraldi-Roux,Morgane Bayle,Céline M'Kadmi,Marjorie Damian,Justine Vaillé,Gimena Fernandez,Maria Paula Cornejo,Jacky Marie,Jean-Louis Banères,Khoubaib Ben Haj Salah,Jean-Alain Fehrentz,Sonia Cantel,Mario Perello,Séverine Denoyelle,Catherine Oiry,Jérémie Neasta +15 more
TL;DR: In this paper , a triazole-derived modulator of growth hormone secretagogue receptor (GHSR) is proposed to mitigate several pathological features associated with eating and metabolic disorders.