M
Muin J. Khoury
Researcher at Centers for Disease Control and Prevention
Publications - 523
Citations - 40286
Muin J. Khoury is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Population & Public health. The author has an hindex of 105, co-authored 512 publications receiving 37434 citations. Previous affiliations of Muin J. Khoury include United States Department of Health and Human Services & Université de Montréal.
Papers
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Genetic and Epidemiologic Approaches to the Search for Gene-Environment Interaction: The Case of Osteoporosis
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Can maternal risk factors influence the presence of major birth defects in infants with Down syndrome
Muin J. Khoury,J D Erickson +1 more
TL;DR: It is suggested that the role of environmental factors and maternal exposures be specifically explored in clarifying the genesis of various birth defects in Down syndrome.
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Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs
TL;DR: The method developed in this paper provides a simple and rigorous first step towards this goal of integrative research, i.e., research that integrates knowledge, data, methods, techniques, and reasoning from multiple disciplines, approaches and levels of analysis to generate knowledge that no discipline alone may achieve.
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The arrival of genomic medicine to the clinic is only the beginning of the journey
James P. Evans,Muin J. Khoury +1 more
TL;DR: The authors detail many of the challenges to using genomics in clinical care and highlight four specific applications of genomics: tumor-based screening, family history–directed decision support, pharmacogenomics (PGx), and diagnostic genome sequencing to demonstrate that genomic medicine is no longer on the threshold; it has arrived.