M
Mukesh K. Jain
Researcher at Kalinga Institute of Medical Sciences
Publications - 577
Citations - 32319
Mukesh K. Jain is an academic researcher from Kalinga Institute of Medical Sciences. The author has contributed to research in topics: Gene & Transcription factor. The author has an hindex of 85, co-authored 539 publications receiving 27485 citations. Previous affiliations of Mukesh K. Jain include Alcan & Indian Institutes of Technology.
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NGS QC Toolkit: a toolkit for quality control of next generation sequencing data.
Ravi K. Patel,Mukesh K. Jain +1 more
TL;DR: The toolkit is comprised of user-friendly tools for QC of sequencing data generated using Roche 454 and Illumina platforms, and additional tools to aid QC (sequence format converter and trimming tools) and analysis and analysis (statistics tools).
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Validation of housekeeping genes as internal control for studying gene expression in rice by quantitative real-time PCR
TL;DR: The expression of UBQ5 and eEF-1alpha was most stable across all the tissue samples examined, however, 18S and 25S rRNA exhibited most stable expression in plants grown under various environmental conditions.
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Anti-inflammatory effects of statins: clinical evidence and basic mechanisms.
Mukesh K. Jain,Paul M. Ridker +1 more
TL;DR: Clinical and experimental evidence underlying the anti-inflammatory effects of statins are discussed, suggesting that these medications have potent anti- inflammatory effects that contribute to their beneficial effects in patients.
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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2
Kush M. Parmar,H. Benjamin Larman,Guohao Dai,Yuzhi Zhang,Eric T. Wang,Sripriya N. Moorthy,Johannes R. Kratz,Zhiyong Lin,Mukesh K. Jain,Michael A. Gimbrone,Guillermo García-Cardeña +10 more
TL;DR: KLF2 therefore serves as a mechano-activated transcription factor important in the integration of multiple endothelial functions associated with regions of the arterial vasculature that are relatively resistant to atherogenesis.
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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation.
Sucharita SenBanerjee,Zhiyong Lin,G. Brandon Atkins,Daniel Greif,Ravi M. Rao,Ajay Kumar,Mark W. Feinberg,Zhiping Chen,Daniel I. Simon,F. William Luscinskas,Thomas Michel,Michael A. Gimbrone,Guillermo García-Cardeña,Mukesh K. Jain +13 more
TL;DR: The studies implicate recruitment by KLF2 of the transcriptional coactivator cyclic AMP response element–binding protein (CBP/p300) as a unifying mechanism for these various effects of proinflammatory stimuli.