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Muriel Golzio

Researcher at University of Toulouse

Publications -  124
Citations -  5610

Muriel Golzio is an academic researcher from University of Toulouse. The author has contributed to research in topics: Electroporation & Gene electrotransfer. The author has an hindex of 35, co-authored 119 publications receiving 4908 citations. Previous affiliations of Muriel Golzio include Paul Sabatier University & Centre national de la recherche scientifique.

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Mechanisms of cell membrane electropermeabilization : A minireview of our present (lack of ?) knowledge

TL;DR: The present state of the investigations concerning the different steps in the reversible electropermeabilization process is described and the different hypotheses, which were proposed to give a molecular description of the membrane events, are critically discussed.
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In vivo electrically mediated protein and gene transfer in murine melanoma.

TL;DR: It is shown that efficient permeabilization of murine melanoma can be obtained in vivo by applying electric pulses and is potentially applicable to a wide variety of tissues, cell types, and animals.
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Direct visualization at the single-cell level of electrically mediated gene delivery

TL;DR: This investigation studies the electropermeabilization process at the single-cell level by using digitized fluorescence microscopy, which shows that membrane-associated spots are formed only when pulses with a longer duration than a critical value are applied.
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Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.

TL;DR: It is shown that adipocytes secrete exosomes in abundance, which are then taken up by tumor cells, leading to increased migration and invasion, and inhibition of this metabolic pathway completely abrogates the exosome-mediated increase in migration.
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Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models.

TL;DR: The first in vivo demonstration of SphK1 as a sensor of chemotherapy is provided, accompanied by a smaller tumor volume and the reduced occurrence and number of metastases in prostate cancer cells implanted in animals.