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Mutasem O. Taha

Researcher at University of Jordan

Publications -  167
Citations -  3542

Mutasem O. Taha is an academic researcher from University of Jordan. The author has contributed to research in topics: Pharmacophore & Quantitative structure–activity relationship. The author has an hindex of 30, co-authored 152 publications receiving 2806 citations. Previous affiliations of Mutasem O. Taha include Loughborough University & Applied Science Private University.

Papers
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Journal ArticleDOI

Degradability of chitosan micro/nanoparticles for pulmonary drug delivery.

Nazrul Islam, +2 more
- 01 May 2019 - 
TL;DR: The synthesis and degradation mechanisms of chitosan micro/nanoparticles frequently used in drug delivery especially in pulmonary drug delivery are reviewed to understand whether these nanoparticles are biodegradable.
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Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2.

Ma'mon M. Hatmal, +9 more
- 08 Dec 2020 - 
TL;DR: This review comprehensively addresses in detail the variations in S protein, its receptor-binding characteristics and detailed structural interactions, the process of cleavage involved in priming, as well as other differences between coronaviruses.
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Synthesis of chitosan succinate and chitosan phthalate and their evaluation as suggested matrices in orally administered, colon-specific drug delivery systems.

Khaled Aiedeh, +1 more
- 01 Mar 1999 - 
TL;DR: The results suggest the suitability of the prepared matrices in colon specific, orally administered drug delivery system, however, future in vivo testing is planned to fully establish the suitabilities of the Prepared polymers for colon‐specific drug delivery.
Journal ArticleDOI

Pharmacophore modeling, quantitative structure-activity relationship analysis, and in silico screening reveal potent glycogen synthase kinase-3beta inhibitory activities for cimetidine, hydroxychloroquine, and gemifloxacin

Mutasem O. Taha, +6 more
- 07 Mar 2008 - 
TL;DR: Docking studies supported the binding modes suggested by the pharmacophore/QSAR analysis, suggesting the existence of at least two distinct binding modes accessible to ligands within GSK-3beta binding pocket.
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Inhibition of glycogen synthase kinase by curcumin: Investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation.

Yasser Bustanji, +5 more
- 27 May 2009 - 
TL;DR: In vivo experiments illustrated that curcumin significantly increases liver glycogen in fasting Balb/c mice and strongly suggest that the diverse pharmacological activities ofCurcumin are at least partially mediated by inhibition of GSK-3β.