Synthesis, antimicrobial and antifungal activity of a new class of spiro pyrrolidines.

This work reviews the use of terpenes available from renewable resources in the fine chemicals industry. Different products and processes are discussed. Transformations of terpenes involving isomerization, hydration, condensation, hydroformylation, hydrogenation, cyclization, oxidation, rearrangement, and ring contraction/enlargement are routes to produce a variety of compounds of interest to the pharmaceutical, agrochemical, and flavors and fragrances industries.

Catalytic Conversion of Terpenes into Fine Chemicals

First Examples of Alkenyl Pyridines as Organic Ligands for Phosphorescent Iridium Complexes

Focusing on the recent literature (since 2000), this review outlines the main synthetic approaches for the preparation of 5′-mono-, 5′-di-, and 5′-triphosphorylated nucleosides, also known as nucleotides, as well as several derivatives, namely, cyclic nucleotides and dinucleotides, dinucleoside 5′,5′-polyphosphates, sugar nucleotides, and nucleolipids. Endogenous nucleotides and their analogues can be obtained enzymatically, which is often restricted to natural substrates, or chemically. In chemical synthesis, protected or unprotected nucleosides can be used as the starting material, depending on the nature of the reagents selected from P(III) or P(V) species. Both solution-phase and solid-support syntheses have been developed and are reported here. Although a considerable amount of research has been conducted in this field, further work is required because chemists are still faced with the challenge of developing a universal methodology that is compatible with a large variety of nucleoside analogues.

Recent Trends in Nucleotide Synthesis.

Advances in Induction and Microwave Heating of Mineral and Organic Materials

High chemoselectivity in microwave accelerated intramolecular domino Knoevenagel hetero Diels–Alder reactions—an efficient synthesis of pyrano[3-2c]coumarin frameworks

Highly chemoselective coupling of allenylstannanes with organic iodides promoted by Pd(PPh3)4/LiCl: an efficient method for the synthesis of substituted allenes

High, Exoselective Diels–Alder Reaction in 5.0M Lithium Perchlorate in Diethyl Ether Medium: Efficient Synthesis of Novel Heterocyclic Derivatives Containing a Spirobicyclo[2.2.1]heptane System

Synthesis of a series of novel 1,3-diphenyl-4-aryl spiropyrazolines [5.3′] 4′-chromanones has been accomplished in good yields by regioselective 1,3-dipolar cycloaddition of diphenylnitrilimine to 3-arylidene-4-chromanones. X-ray crystal structure analysis of one of the products 4a confirms the structure and the regiochemistry of cycloaddition. © 1998 John Wiley & Sons, Inc. Heteroatom Chem 9:327–332, 1998

Muthian Shanmugasundaram

Papers

High chemoselectivity in microwave accelerated intramolecular domino Knoevenagel hetero Diels–Alder reactions—an efficient synthesis of pyrano[3-2c]coumarin frameworks

Highly chemoselective coupling of allenylstannanes with organic iodides promoted by Pd(PPh3)4/LiCl: an efficient method for the synthesis of substituted allenes

High, Exoselective Diels–Alder Reaction in 5.0M Lithium Perchlorate in Diethyl Ether Medium: Efficient Synthesis of Novel Heterocyclic Derivatives Containing a Spirobicyclo[2.2.1]heptane System

Synthesis of spiropyrazoline [5.3′] 4′-chromanones

Competition between two intramolecular domino Knoevenagel hetero Diels-Alder reactions: a new entry into novel pyranoquinolinone derivatives