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N. Di Lorenzo
Researcher at University of Florence
Publications - 31
Citations - 681
N. Di Lorenzo is an academic researcher from University of Florence. The author has contributed to research in topics: Hydrocephalus & Syringomyelia. The author has an hindex of 14, co-authored 30 publications receiving 622 citations.
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hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines
Alessio Masi,Andrea Becchetti,Rita Restano-Cassulini,Simone Polvani,Giovanna Hofmann,Annamaria Buccoliero,Milena Paglierani,B Pollo,Gianluigi Taddei,Pasquale Gallina,N. Di Lorenzo,Silvana Franceschetti,Enzo Wanke,Annarosa Arcangeli +13 more
TL;DR: HERG1 was found to be specifically overexpressed in high-grade astrocytomas, that is, glioblastoma multiforme (GBM), and evidence that, in GBM cell lines, hERG1 channel activity actively contributes to malignancy by promoting vascular endothelial growth factor secretion, thus stimulating the neoangiogenesis typical of high-grades gliomas.
Journal Article
Diagnostic therapeutic flow-charts for low back pain patients: the Italian clinical guidelines
Stefano Negrini,S. Giovannoni,Silvia Minozzi,G. Barneschi,D. Bonaiuti,A. Bussotti,M. D'Arienzo,N. Di Lorenzo,A. Mannoni,Stefano Mattioli,V. Modena,Luca Padua,F. Serafini,Francesco Saverio Violante +13 more
TL;DR: The DTF, that were produced in a strictly evidence-based way, have been considered by the IHM a subsequent step, more concrete and operative (almost clinical-care profiles) with respect to the classic Guidelines.
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Ascending myelopathy in the early stage of spinal cord injury.
TL;DR: The presenting author stresses the importance of adopting MRI-compatible instrumentation for the surgical stabilisation of the spine, and careful monitoring of blood pressure during the acute phase of spinal cord injury.
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Changes in aqueductal CSF stroke volume in shunted patients with idiopathic normal-pressure hydrocephalus.
Antonio Scollato,Pasquale Gallina,B. Gautam,G. Pellicano,C. Cavallini,R. Tenenbaum,N. Di Lorenzo +6 more
TL;DR: ACSV decreases in all patients in whom the VPS system works properly, with the rate of ACSV decrease being higher in the patients who show clinical improvement, and postoperative ACSV increase suggests shunt malfunction.
Journal ArticleDOI
Extra-arachnoidal cranio-cervical decompression for syringomyelia associated with Chiari I malformation in adults : technique assessment
TL;DR: The extra-arachnoidal cranio-cervical decompression (CCD) without duroplasty is a safe and effective treatment for syringomyelia associated with Chiari I malformation in adults without intraoperative evidence of adhesive arachnoiditis, however a larger number of patients and longer follow-up will be necessary to determine the efficacy.