N. Franklin Adkinson

TL;DR: Under the conditions of this study, the current standard method of immunotherapy produced a significant decrease in ragweed hay fever symptom-medication scores, increase in antiragweed IgG levels, and decrease in seasonal rise in antigweed IgE levels in comparison with the effects of either Rinkel method or placebo.

TL;DR: In 10 patients with cat asthma and hay fever, the doses of cat allergen (expressed as Cat-1] in log Food and Drug Administration units) inspired from the ambient air of a room containing living cats required to induce a 20% drop in FEV1 were quantified.

TL;DR: The optimal individual treatment dose of ragweed extract for immunotherapy at greater than 0.6 micrograms, but probably not more than 12.4micrograms in terms of Amb a I equivalents is set.

TL;DR: Treatment failures on Rinkel immunotherapy respond well to adequate dose immunotherapy by either schedule, and patients after adequate treatment with either RW-Wk or RW-Cl have significantly lower symptom-medication scores than those of the placebo groups and immunologic changes similar toThose of the entire active-treatment group.

TL;DR: Rinkel method immunotherapy with ragweed pollen extract was no more effective than placebo given in an imitation of the Rinkel method, and despite the absence of specific effect on symptom-medication scores and measured immunologic variates, 10 of the 12 ragweed-treated patients were of the opinion that their hay fever symptoms during the rag weed pollen season were less severe in 1978 than in 1977 and that they had been helped by Rinkel process immunotherapy.