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N. Franklin Adkinson
Researcher at Johns Hopkins University
Publications - 141
Citations - 11821
N. Franklin Adkinson is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Immunoglobulin E & Histamine. The author has an hindex of 47, co-authored 140 publications receiving 11073 citations. Previous affiliations of N. Franklin Adkinson include Johns Hopkins University School of Medicine & Good Samaritan Hospital.
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Journal ArticleDOI
Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.
Thomas J. Povsic,Monica G. Lawrence,A. Michael Lincoff,Roxana Mehran,Christopher P. Rusconi,Steven L. Zelenkofske,Zhen Huang,Jeffrey Sailstad,Paul W. Armstrong,P. Gabriel Steg,P. Gabriel Steg,Christoph Bode,Richard C. Becker,John H. Alexander,N. Franklin Adkinson,Arnold I. Levinson +15 more
TL;DR: Pegnivacogin should undergo additional definitive testing incorporating a risk mitigation and action plan in a phase III trial to Determine the Efficacy and Safety of the REG1 Anticoagulation System Compared to Bivalirudin in Patients Undergoing Percutaneous Coronary Intervention.
Journal ArticleDOI
Cornstarch powder on latex products is an allergen carrier.
Vesna J. Tomazic,Eric L. Shampaine,Anthony Lamanna,Thomas J. Withrow,N. Franklin Adkinson,Robert G. Hamilton +5 more
TL;DR: It is demonstrated that cornstarch indeed binds allergenic latex proteins and supports the causative relationship between allergic reactions in individuals with latex sensitivity and the exposure to airborne particles from powdered latex products.
Journal ArticleDOI
Immunotherapy for cat asthma
Thomas E. Van Metre,Thomas E. Van Metre,David G. Marsh,David G. Marsh,N. Franklin Adkinson,N. Franklin Adkinson,Anne Kagey-Sobotka,Anne Kagey-Sobotka,Arouna Khattignavong,Arouna Khattignavong,Philip S. Norman,Philip S. Norman,Gary L. Rosenberg,Gary L. Rosenberg +13 more
TL;DR: It is concluded that cat-extract immunotherapy was well tolerated, significantly decreased skin and bronchial responses to cat extract, and significantly increased IgE antibodies to cat Extract and IgG antibodies toCat extract, Fel d I, and cat albumin.
Journal ArticleDOI
Risk factors for drug allergy
TL;DR: The elicitation of drug-induced immunopathology is a function of the persistence of a drug-specific immune response; the frequency of drug treatment and its dose and duration; and probable constitutional factors that may determine in an important way the efficiency with which aDrug- specific immune response can be translated into a systemic allergic reaction.
Journal ArticleDOI
Penicillin Allergy Is Not Necessarily Forever
TL;DR: The inability to use an antistaphylococcal penicillin for patients with methicillin-susceptible StAPHylococcus aureus sepsis or other serious infections for which penicillins are the first-line therapy places patients at risk of treatment failure, resistance generation, and increased mortality.