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N.J. Cochrane
Researcher at University of Melbourne
Publications - 28
Citations - 2278
N.J. Cochrane is an academic researcher from University of Melbourne. The author has contributed to research in topics: Enamel paint & Amorphous calcium phosphate. The author has an hindex of 19, co-authored 28 publications receiving 1995 citations. Previous affiliations of N.J. Cochrane include Cooperative Research Centre.
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Journal ArticleDOI
New Approaches to Enhanced Remineralization of Tooth Enamel
TL;DR: Biomimetic approaches to stabilization of bioavailable calcium, phosphate, and fluoride ions and the localization of these ions to non-cavitated caries lesions for controlled remineralization show promise for the non-invasive management of dental caries.
Journal ArticleDOI
Fluoride and Casein Phosphopeptide-Amorphous Calcium Phosphate
Eric C. Reynolds,F. Cai,N.J. Cochrane,Peiyan Shen,Glenn D Walker,Mike Morgan,Coralie Reynolds +6 more
TL;DR: The addition of 2% CPP-ACP to the 450-ppm-F mouthrinse significantly increased the incorporation of fluoride into plaque and produced a level of remineralization similar to that achieved with a dentifrice containing 2800 ppm F.
Journal ArticleDOI
Enamel subsurface lesion remineralisation with casein phosphopeptide stabilised solutions of calcium, phosphate and fluoride.
TL;DR: The activity gradient of the neutral ion pair CaHPO4⁰ into the lesion was significantly correlated with remineralisation and together with HF⁰ were identified as important species for diffusion.
Journal ArticleDOI
Calcium phosphopeptides -- mechanisms of action and evidence for clinical efficacy.
N.J. Cochrane,Eric C. Reynolds +1 more
TL;DR: casein phosphopeptide-stabilized amorphous calcium phosphate nanocomplexes (CPP-ACP) can stabilize even higher concentrations of calcium and phosphate than milk and can be considered a salivary biomimetic, since they share many similarities to statherin.
Journal ArticleDOI
Effect of added calcium phosphate on enamel remineralization by fluoride in a randomized controlled in situ trial
Peiyan Shen,David J. Manton,N.J. Cochrane,Glenn D Walker,Yi Yuan,Coralie Reynolds,Eric C. Reynolds +6 more
TL;DR: Comparing remineralization of enamel subsurface lesions by dental products with added calcium phosphate and fluoride in a double-blind, randomized, cross-over in situ study found Clinpro was not significantly different to 1000 ppm F whereas TM and TMP were superior to 5000 ppm F with TMP producing the highest level ofEnamel lesion reminalization.