Textbook of biochemistry with clinical correlations , 4th edn TM Devlin, ed pp xvii + 1186, illustrated Wiley-Liss, New York, 1997 £2995, hardback

This beautifully illustrated and well-written book, with an impressive array of authors, is aimed at both undergraduate and postgraduate level As the editor states in the preface, it is not intended to be a compendium of biochemistry but rather emphasises the biochemistry of mammalian cells The first 22 chapters cover …

Textbook of biochemistry with clinical correlations

Background Thymus genus has been used since ancient times for their valuable health properties, which could be attributed to their chemical components, especially essential oils (EOs). Among these species, T. vulgaris has a long history of use for different food and medicinal purposes. Scope and approach This paper reviews the chemical composition of Thymus plants EOs, including thyme, describes their antimicrobial and antioxidant properties as well as recent food applications as preservatives. The role of these plants in cancer is also covered, as well as the potential these plants have to manage and treat other diseases. Furthermore, clinical studies are also detailed. Key findings and conclusions Food preservation with naturally occurring compounds is gaining increasing importance due to the consumer demand for safe and high-quality products and to reduce the use of synthetic preservatives. For this purpose, not only thyme but also other thymus plants can be used as such and combined with high-pressure, cold nitrogen plasma, in edible films (active packaging), etc. Moreover, the potential of these plants have to treat several diseases and complications reinforce their use in nutraceuticals and functional foods, but further clinical evidence is required.

Thymus spp. plants - Food applications and phytopharmacy properties

A systematic review on ethnopharmacology, phytochemistry and pharmacological aspects of Thymus vulgaris Linn.

The inhibitory activity toward human leukocyte elastase (HLE), cathepsin G (Cat G), and proteinase 3 (PR 3) of a series of saccharin derivatives having a sulfinate leaving group was investigated. The results of this study revealed that (a) inhibitory activity is dependent on the nature and pKa of the leaving group, and (b) the synthesized saccharin derivatives exhibit selective inhibition toward HLE and PR 3, with low or no activity toward cathepsin G. The results of exploratory biochemical, HPLC and high-field 13C NMR studies are also described.

Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners

The influence of different extraction conditions on polyphenol content, antioxidant and antimicrobial activities of wild thyme

Isolation had been done for active substances from Thyme plant (Thymus Vulgaris) such as volatile oils, Saponins and Tannins. The percentage in form was (21.1%),(59.2%),( 9.7%) respectively. Also a study of anti-bacterial activity of extracts from Thyme using two types of pathogenic bacteria Escherichia Coli and aurous Staphylococcus showed the ability of inhibition for all different extracts by vary inhibition diameters for different active substances, concentrations and bacteria. One type of cancer cellular line used to study the effect of Thyme  extracts on the growth of cells in the laboratory and thus know the specifications of extracts as anti-tumor, (L 20 B) cell line have been used which  is mice Transformed cell Line. The possibility of using alcohol extract as anti-oxidant to be add to ghee or vegetable oil, the sensory evaluation and physical results were very good over full year. Keywords : Thymus Vulgaris, Antibacterial and  anticancer activity. Extraction, Anti-Oxidant

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Water And Alcohol Extraction Of Thyme Plant (Thymus Vulgaris) And Activity Study Against Bacteria, Tumors And Used As Anti-Oxidant In Margarine Manufacture

The mixed ligand complexes of Mn(II),Fe(II ), Co(II),Ni(II),Cu(II), Zn(II) and Cd (II) with 1-nitroso-2-naphthol (C 10 H 7 NO 2 ), symbolized (NNPhH)] and amino acid L-phenylalanine ( C 9 H 10 NO 2 ) , symbolized ( phe H),  were synthesized and characterized by: Melting points, Solubility, Molar conductivity. determination the percentage of the metal in the complexes by flame(AAS), Molecular weight determined by  Rast’s Camphor method, susceptibility measurements, Spectroscopic Method [FT-IR and UV-Vis], And Program  [Chem office– CS .Chem.– 3D pro 2006] was used for draw compounds . The results showed that the deprotonated   two  ligands acts as a bidentate ligand ,  ( phe - ) was coordinated to the metal ions through the oxygen  of  the  carboxylic  group  and  the nitrogen of the amine and  the 1-nitroso-2-naphthol ligand was coordinated to the metal ions through the oxygen and nitrogen atoms. The electronic absorption spectra and magnetic susceptibility measurements of the complexes indicate octahedral geometry for all the complexes. Key words: phenyl alanine , amino acid) Complexes ,  1-nitroso-2-naphthol  ,mixed ligands   and Antibacterial     Activities

/pdf/synthesis-characterization-and-antibacterial-activity-of-13zm2r3xi9.pdf

Synthesis ,characterization and antibacterial activity of mixed ligand complexes of some metals with 1-nitroso-2-naphthol and L-phenylalanine

A new six mixed ligand complexes of some transition metal ions Manganese (II), Cobalt(II), Iron (II), Nickel (II) , and non transition metal ion zinc (II) And Cadmium(II) with L-valine (Val H ) as a primary ligand and Saccharin (HSac)  as a secondary ligands  have been prepared. All the prepared complexes have been characterized by molar conductance, magnetic susceptibility infrared, electronic spectral, Elemental microanalysis (C.H.N ) and AA . The complexes with the formulas   [M(Val) 2 (HSac) 2 ] M= Mn (II) , Fe (II) , Co(II) ,Ni(II), Cu (II),Zn(II) and  Cd(II) L- Val H= (C 5 H 11 NO 2 )  , C 7 H 5 NO 3 S The study shows that these complexes have octahedral geometry; The metal complexes have been screened for their in microbiological activities against bacteria.  Based on the reported results, it may be concluded that the deprotonated ligand  (L-valine) to (valinate ion (Val - )  by using (Na OH) coordinated to metal ions as bidentate ligand through the oxygen atom of the carboxylate group(-COO - ), and the nitrogen atom of the amine group (NH 2 ), where the saccharin (H Sac) coordinated as a monodentate through the nitrogen atom. Keywords : L-Valine , mixed ligand complexes, Saccharin  , spectral studies , Antibacterial activities.

https://www.iiste.org/Journals/index.php/APTA/article/download/2938/2980

Synthesis, Characterization, And Antibacterial Activities Of Manganese (II), Cobalt(II), Iron (II), Nickel (II) , zinc (II) And Cadmium(II) Mixed- Ligand Complexes Containing Amino Acid(L-Valine) And Saccharin

N.K. Fayad

Papers

Water And Alcohol Extraction Of Thyme Plant (Thymus Vulgaris) And Activity Study Against Bacteria, Tumors And Used As Anti-Oxidant In Margarine Manufacture

Synthesis ,characterization and antibacterial activity of mixed ligand complexes of some metals with 1-nitroso-2-naphthol and L-phenylalanine

Synthesis, Characterization, And Antibacterial Activities Of Manganese (II), Cobalt(II), Iron (II), Nickel (II) , zinc (II) And Cadmium(II) Mixed- Ligand Complexes Containing Amino Acid(L-Valine) And Saccharin