다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

The PASCAL Visual Object Classes Challenge

Matrix Differential Calculus with Applications in Statistics and Econometrics

Deep learning describes a class of machine learning algorithms that are capable of combining raw inputs into layers of intermediate features. These algorithms have recently shown impressive results across a variety of domains. Biology and medicine are data-rich disciplines, but the data are complex and often ill-understood. Hence, deep learning techniques may be particularly well suited to solve problems of these fields. We examine applications of deep learning to a variety of biomedical problems-patient classification, fundamental biological processes and treatment of patients-and discuss whether deep learning will be able to transform these tasks or if the biomedical sphere poses unique challenges. Following from an extensive literature review, we find that deep learning has yet to revolutionize biomedicine or definitively resolve any of the most pressing challenges in the field, but promising advances have been made on the prior state of the art. Even though improvements over previous baselines have been modest in general, the recent progress indicates that deep learning methods will provide valuable means for speeding up or aiding human investigation. Though progress has been made linking a specific neural network's prediction to input features, understanding how users should interpret these models to make testable hypotheses about the system under study remains an open challenge. Furthermore, the limited amount of labelled data for training presents problems in some domains, as do legal and privacy constraints on work with sensitive health records. Nonetheless, we foresee deep learning enabling changes at both bench and bedside with the potential to transform several areas of biology and medicine.

https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2017.0387

Opportunities and obstacles for deep learning in biology and medicine.

Uncertainty quantification (UQ) plays a pivotal role in reduction of uncertainties during both optimization and decision making processes. It can be applied to solve a variety of real-world applications in science and engineering. Bayesian approximation and ensemble learning techniques are two most widely-used UQ methods in the literature. In this regard, researchers have proposed different UQ methods and examined their performance in a variety of applications such as computer vision (e.g., self-driving cars and object detection), image processing (e.g., image restoration), medical image analysis (e.g., medical image classification and segmentation), natural language processing (e.g., text classification, social media texts and recidivism risk-scoring), bioinformatics, etc. This study reviews recent advances in UQ methods used in deep learning. Moreover, we also investigate the application of these methods in reinforcement learning (RL). Then, we outline a few important applications of UQ methods. Finally, we briefly highlight the fundamental research challenges faced by UQ methods and discuss the future research directions in this field.

A Review of Uncertainty Quantification in Deep Learning: Techniques, Applications and Challenges

Melanoma, most threatening type of skin cancer, is on the rise. In this paper an implementation of a deep-learning system on a computer server, equipped with graphic processing unit (GPU), is proposed for detection of melanoma lesions. Clinical (non-dermoscopic) images are used in the proposed system, which could assist a dermatologist in early diagnosis of this type of skin cancer. In the proposed system, input clinical images, which could contain illumination and noise effects, are preprocessed in order to reduce such artifacts. Afterward, the enhanced images are fed to a pre-trained convolutional neural network (CNN) which is a member of deep learning models. The CNN classifier, which is trained by large number of training samples, distinguishes between melanoma and benign cases. Experimental results show that the proposed method is superior in terms of diagnostic accuracy in comparison with the state-of-the-art methods.

Melanoma detection by analysis of clinical images using convolutional neural network

Population of old generation is growing in most countries. Many of these seniors are living alone at home. Falling is among the most dangerous events that often happen and may need immediate medical care. Automatic fall detection systems could help old people and patients to live independently. Vision-based systems have advantage over wearable devices. These visual systems extract some features from video sequences and classify fall and normal activities. These features usually depend on camera's view direction. Using several cameras to solve this problem increases the complexity of the final system. In this paper, we propose to use variations in silhouette area that are obtained from only one camera. We use a simple background separation method to find the silhouette. We show that the proposed feature is view invariant. Extracted feature is fed into a support vector machine for classification. Simulation of the proposed method using a publicly available dataset shows promising results.

Automatic Monocular System for Human Fall Detection Based on Variations in Silhouette Area

Colorectal cancer is one of the highest causes of cancer-related death, especially in men. Polyps are one of the main causes of colorectal cancer, and early diagnosis of polyps by colonoscopy could result in successful treatment. Diagnosis of polyps in colonoscopy videos is a challenging task due to variations in the size and shape of polyps. In this paper, we proposed a polyp segmentation method based on the convolutional neural network. Two strategies enhance the performance of the method. First, we perform a novel image patch selection method in the training phase of the network. Second, in the test phase, we perform effective post-processing on the probability map that is produced by the network. Evaluation of the proposed method using the CVC-ColonDB database shows that our proposed method achieves more accurate results in comparison with previous colonoscopy video-segmentation methods.

Polyp Segmentation in Colonoscopy Images Using Fully Convolutional Network

Melanoma is the most aggressive form of skin cancer and is on rise. There exists a research trend for computerized analysis of suspicious skin lesions for malignancy using images captured by digital cameras. Analysis of these images is usually challenging due to existence of disturbing factors such as illumination variations and light reflections from skin surface. One important stage in diagnosis of melanoma is segmentation of lesion region from normal skin. In this paper, a method for accurate extraction of lesion region is proposed that is based on deep learning approaches. The input image, after being preprocessed to reduce noisy artifacts, is applied to a deep convolutional neural network (CNN). The CNN combines local and global contextual information and outputs a label for each pixel, producing a segmentation mask that shows the lesion region. This mask will be further refined by some post processing operations. The experimental results show that our proposed method can outperform the existing state-of-the-art algorithms in terms of segmentation accuracy.

Skin lesion segmentation in clinical images using deep learning

Due to the rapid growth of machine learning tools and specifically deep networks in various computer vision and image processing areas, applications of Convolutional Neural Networks for watermarking have recently emerged. In this paper, we propose a deep end-to-end diffusion watermarking framework (ReDMark) which can learn a new watermarking algorithm in any desired transform space. The framework is composed of two Fully Convolutional Neural Networks with residual structure which handle embedding and extraction operations in real-time. The whole deep network is trained end-to-end to conduct a blind secure watermarking. The proposed framework simulates various attacks as a differentiable network layer to facilitate end-to-end training. The watermark data is diffused in a relatively wide area of the image to enhance security and robustness of the algorithm. Comparative results versus recent state-of-the-art researches highlight the superiority of the proposed framework in terms of imperceptibility, robustness and speed. The source codes of the proposed framework are publicly available at Github 1 .

Nader Karimi

Papers

Melanoma detection by analysis of clinical images using convolutional neural network

Automatic Monocular System for Human Fall Detection Based on Variations in Silhouette Area

Polyp Segmentation in Colonoscopy Images Using Fully Convolutional Network

Skin lesion segmentation in clinical images using deep learning

ReDMark: Framework for Residual Diffusion Watermarking based on Deep Networks