N
Naoko Watanabe
Researcher at Tokyo University of Science
Publications - 5
Citations - 382
Naoko Watanabe is an academic researcher from Tokyo University of Science. The author has contributed to research in topics: Cell culture & Cellular differentiation. The author has an hindex of 4, co-authored 5 publications receiving 362 citations. Previous affiliations of Naoko Watanabe include University of Tokyo.
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Journal ArticleDOI
Stimulation of osteoblastic cell differentiation by Notch.
Ken-ichi Tezuka,Masafumi Yasuda,Naoko Watanabe,Naoko Morimura,Kazuki Kuroda,Seiji Miyatani,Nobumichi Hozumi +6 more
TL;DR: Observations suggest that osteoblastic cell differentiation is regulated positively by Notch and that Notch could be a unique and interesting target molecule for the treatment of osteoporosis.
Journal ArticleDOI
Suppression of differentiation and proliferation of early chondrogenic cells by Notch.
Naoko Watanabe,Yoko Tezuka,Kenji Matsuno,Seiji Miyatani,Naoko Morimura,Masafumi Yasuda,Ryoji Fujimaki,Kazuki Kuroda,Yuji Hiraki,Nobumichi Hozumi,Ken-ichi Tezuka +10 more
TL;DR: The results indicate that Notch is expressed in the initial stage of chondrogenic cell differentiation and has a strong inhibitory effect on both differentiation and proliferation of the cells when activated.
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Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin.
Naoko Morimura,Yoko Tezuka,Naoko Watanabe,Masafumi Yasuda,Seiji Miyatani,Nobumichi Hozumi,Ken-ichi Tezuka +6 more
TL;DR: The results suggest that POEM is a novel ligand for α8β1integrin and thatPOEM may be involved in the development and function of various tissues, such as kidney, bone, muscles, and endocrine organs.
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Expression of Cre recombinase in the mouse developing chondrocytes driven by the mouse α2(XI) collagen promoter
Ryoji Fujimaki,Katsuhiko Hayashi,Naoko Watanabe,Taketo Yamada,Yoshiaki Toyama,Ken-ichi Tezuka,Nobumichi Hozumi +6 more
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Use of the SST-REX method for the identification of genes expressed at the condensation stage of chondrogenic cell line ATDC5
Atsushi Noguchi,Naoko Watanabe,Ryoji Fujimaki,Toshio Kitamura,Yoshihide Hayashizaki,Shigeru Miyaki,Ken-ichi Tezuka,Nobumichi Hozumi +7 more
TL;DR: The results demonstrate that the SST–REX method is a useful experimental system to identify genes involved in the complicated mechanisms of bone formation.