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Nat N. V. Kav
Researcher at University of Alberta
Publications - 78
Citations - 2997
Nat N. V. Kav is an academic researcher from University of Alberta. The author has contributed to research in topics: Sclerotinia sclerotiorum & Gene. The author has an hindex of 30, co-authored 72 publications receiving 2567 citations.
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Journal ArticleDOI
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Tiziana Sonati,Regina Reimann,Jeppe Falsig,Pravas Kumar Baral,Tracy O'Connor,Simone Hornemann,Sine Yaganoglu,Bei Li,Uli S. Herrmann,Barbara Wieland,Mridula Swayampakula,Muhammad H. Rahman,Dipankar Das,Nat N. V. Kav,Roland Riek,Pawel P. Liberski,Michael N.G. James,Adriano Aguzzi +17 more
TL;DR: In this article, the authors describe rapid neurotoxicity in mice and cerebellar organotypic cultured slices exposed to ligands targeting the α1 and α3 helices of the cellular PrP(C) globular domain.
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The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.
Magdalini Polymenidou,Rita Moos,Mike Scott,Christina J. Sigurdson,Yong-zhong Shi,Bill Yajima,Iva Hafner-Bratkovič,Roman Jerala,Simone Hornemann,Kurt Wüthrich,Kurt Wüthrich,Anne Bellon,Martin Vey,Graciela Garen,Michael N.G. James,Nat N. V. Kav,Adriano Aguzzi +16 more
TL;DR: A comprehensive collection of monoclonal antibodies denoted POM1 to POM19 and directed against many different epitopes of mouse PrPC, which represents a unique set of reagents allowing for studies with a variety of techniques, including western blotting, ELISA, immunoprecipitation, conformation-dependent immunoassays, and plasmon surface plasMon resonance-based assays.
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Functional characterization of four APETALA2-family genes (RAP2.6, RAP2.6L, DREB19 and DREB26) in Arabidopsis.
TL;DR: Functional characterization of four AP2 TF family genes are reported, demonstrating that RAP2.6, R.6L, DREB26 and D REB19 are transactivators, they exhibit tissue specific expression, and they participate in plant developmental processes as well as biotic and/or abiotic stress signaling.
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Identification and expression analysis of WRKY transcription factor genes in canola (Brassica napus L.) in response to fungal pathogens and hormone treatments.
TL;DR: This study suggests that a large number of BnWRKY proteins are involved in the transcriptional regulation of defense-related genes in response to fungal pathogens and hormone stimuli.
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Regulation of low temperature stress in plants by microRNAs
TL;DR: The current understanding of miRNA-mediated modulation of the expression of key genes as well as genetic and regulatory pathways, involved in low temperature stress responses in plants are summarized.