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Christina J. Sigurdson

Researcher at University of California, San Diego

Publications -  96
Citations -  12412

Christina J. Sigurdson is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Chronic wasting disease & Amyloid. The author has an hindex of 46, co-authored 88 publications receiving 11086 citations. Previous affiliations of Christina J. Sigurdson include Colorado State University & University of California, Berkeley.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Infectious Prions in the Saliva and Blood of Deer with Chronic Wasting Disease

Candace K. Mathiason, +16 more
- 06 Oct 2006 - 
TL;DR: This paper found infectious prions capable of transmitting chronic wasting disease (CWD) in saliva (by the oral route) and in blood (by transfusion) from CWD-positive deer.
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Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

Mathias Heikenwalder, +7 more
- 01 Feb 2004 - 
TL;DR: It is reported that daily injection of 60 μg CpG-ODN dramatically alters the morphology and functionality of mouse lymphoid organs and strongly reduced primary humoral immune responses and immunoglobulin class switching.
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Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue.

Marius Kollmer, +10 more
- 29 Oct 2019 - 
TL;DR: Cryo-EM is used to structurally characterise brain derived Aβ amyloid fibrils and it is found that they are polymorphic and right-hand twisted, which differs from in vitro generated Aβ fibril.
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Molecular mechanisms of prion pathogenesis

Adriano Aguzzi, +2 more
- 30 Jan 2008 - 
TL;DR: The molecular mechanisms leading to neurodegeneration, the role of the immune system in prion pathogenesis, and the existence of prion strains that appear to have different tropisms and biochemical characteristics are discussed.