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Natalia Tschowri

Researcher at Humboldt University of Berlin

Publications -  27
Citations -  1454

Natalia Tschowri is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Second messenger system & Streptomyces. The author has an hindex of 14, co-authored 22 publications receiving 1238 citations. Previous affiliations of Natalia Tschowri include Free University of Berlin & University of Toronto.

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Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli

TL;DR: The logic and sequence of molecular events underlying the motile-to-adhesive "lifestyle" switch in E. coli are revealed and a fine-tuned checkpoint system that "unlocks" curli expression only after down-regulation of flagellar gene expression is produced.
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Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.

TL;DR: It is reported that c-di-GMP can assemble into a tetramer that mediates the effective dimerization of a transcription factor, BldD, which controls the progression of multicellular differentiation in sporulating actinomycete bacteria.
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The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli

TL;DR: This pathway may modulate biofilm formation via the two-component network when E. coli has to survive in an extrahost aquatic environment through the expression and activity of the YcgF/YcgE/small protein signaling pathway.
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Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli.

TL;DR: A diverse battery of GGDEF/EAL proteins is deployed during entry into stationary phase, especially in cells grown at reduced temperature (28 degrees C), which suggests that multiple signal input into cyclic-di-GMP control is particularly important in growth-restricted cells in an extra-host environment.
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c-di-GMP signalling and the regulation of developmental transitions in streptomycetes.

TL;DR: Important new insights are discussed into the signalling pathways that regulate the developmental transitions leading to sporulation in streptomycetes, focusing on the erection of aerial hyphae and the synchronous cell division event that produces dozens of unigenomic spores.