Showing papers by "Natalia V. Gulyaeva published in 1990"
TL;DR: The aim of this investigation was to study the state of LPO and of the brain lipid composition during training.
Abstract: Lipids play an important role in the function of membranes, for they determine their viscosity, the state of their receptors and ionic channels, and the activity of membrane-bound enzymes [9]. It has been shown that the lipid component of synaptosomes is a modulator of activity of the serotoninergic system [2]. Differences in the lipid composition of the brain have recently been demonstrated in mice selected on the basis of different brain weight and differing in their learning ability [1]. One of the most important processes leading to modification of the lipid component of membrane is free-radical lipid peroxidation (LPO), changes in the intensity of which accompany many changes in brain function [1, 2, 4, 8]. The aim of this investigation was to study the state of LPO and of the brain lipid composition during training.