N
Natalie Sparks
Researcher at University of Birmingham
Publications - 2
Citations - 331
Natalie Sparks is an academic researcher from University of Birmingham. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 1, co-authored 1 publications receiving 130 citations.
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Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore
John R. Tyson,Phillip James,David Stoddart,Natalie Sparks,Arthur Wickenhagen,Grant Hall,Ji Hyun Choi,Hope R. Lapointe,Kimia Kamelian,Andrew D. Smith,Natalie Prystajecky,Ian Goodfellow,Sam J. Wilson,Richard Harrigan,Terrance P. Snutch,Nicholas J. Loman,Joshua Quick +16 more
TL;DR: An updated primer scheme with 22 additional primers to improve genome coverage and cost savings which bring the reagent cost down to £10 per sample making it practical for individual labs to sequence thousands of SARS-CoV-2 genomes to support national and international genomic epidemiology efforts.
Journal ArticleDOI
Recurrent SARS-CoV-2 mutations in immunodeficient patients
Steven Andrew Wilkinson,Alex G. Richter,Anna Casey,Husam Osman,Jeremy Mirza,Joanne Stockton,Joshua Quick,Liz Ratcliffe,Natalie Sparks,Nicola Cumley,Radoslaw Poplawski,Samuel N Nicholls,Beatrix Kele,Kathryn A. Harris,Thomas P. Peacock,Nicholas J. Loman +15 more
TL;DR: A mutation in the envelope gene, - T30I was determined to be the most recurrent frequently occurring mutation arising in persistent infections.