N
Negar Azarpira
Researcher at Shiraz University of Medical Sciences
Publications - 482
Citations - 6293
Negar Azarpira is an academic researcher from Shiraz University of Medical Sciences. The author has contributed to research in topics: Medicine & Transplantation. The author has an hindex of 32, co-authored 413 publications receiving 4298 citations. Previous affiliations of Negar Azarpira include Namazi Hospital & Yahoo!.
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Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine.
TL;DR: MSC-derived extracellular vesicles may be used as an alternative MSC-based therapy in regenerative medicine and their therapeutic potential in various diseases is discussed.
Journal ArticleDOI
Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia.
Akram Jamshidzadeh,Reza Heidari,Mozhgan Abasvali,Mehdi Zarei,Mohammad Mehdi Ommati,Narges Abdoli,Forouzan Khodaei,Yasaman Yeganeh,Faezeh Jafari,Azita Zarei,Zahra Latifpour,Elnaz Mardani,Negar Azarpira,Behnam Asadi,Asma Najibi +14 more
TL;DR: Taurine was found to be a potential protective agent with therapeutic capability against hepatic encephalopathy and hyperammonemia-induced mitochondrial dysfunction and energy crisis and restored brain and liver mitochondrial ATP.
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Effect of taurine on chronic and acute liver injury: Focus on blood and brain ammonia.
Reza Heidari,Akram Jamshidzadeh,Hossein Niknahad,Elnaz Mardani,Mohammad Mehdi Ommati,Negar Azarpira,Forouzan Khodaei,Azita Zarei,Maryam Ayarzadeh,Somayeh Mousavi,Narges Abdoli,Babak Shirazi Yeganeh,Arastoo Saeedi,Asma Najibi +13 more
TL;DR: In this article, the role of taurine (TA) administration on plasma and brain ammonia and its consequent events in different models of chronic and acute liver injury and hyperammonemia was evaluated.
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Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury
Reza Heidari,Hossein Niknahad,Ala Sadeghi,Hamidreza Mohammadi,Vahid Ghanbarinejad,Mohammad Mehdi Ommati,Arghavan Hosseini,Negar Azarpira,Forouzan Khodaei,Omid Farshad,Elaheh Rashidi,Asma Siavashpour,Asma Najibi,Asrin Ahmadi,Akram Jamshidzadeh +14 more
TL;DR: Betaine supplementation ameliorated hepatic injury as judged by decreased liver tissue histopathological alterations, a significant decrease in tissue markers of oxidative stress, and mitigation of serum biomarkers of hepatotoxicity.
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The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative stress.
Reza Heidari,Shima Behnamrad,Zahra Khodami,Mohammad Mehdi Ommati,Negar Azarpira,Afsaneh Vazin +5 more
TL;DR: The data obtained from the current study suggest mitochondrial dysfunction and oxidative stress as fundamental mechanisms of renal injury induced by COL and taurine supplementation protected kidney through decreasing oxidative stress and regulating mitochondrial function.